Health-Related Quality of Life Related to Toxicity Treatments in Central Nervous System Metastases

  • Tobias WalbertEmail author
  • Erika S. Horta


Health-related quality of life (HRQoL) is a multidimensional concept that measures how a disease and the treatment of that disease impact a patient’s life. It can also aid in the dialogue between physician and patient. As different therapies have distinct mechanisms, the HRQoL of a patient might be affected in diverse ways depending on the particular side effects that he or she experiences. This chapter discusses the importance of HRQoL related to treatment toxicity, the different tools that are used to measure this outcome, and how different therapeutic modalities impact the patient with central nervous system (CNS) metastases.


Central nervous system (CNS) Chemotherapy Health-related quality of life (HRQoL) Immunotherapy Metastasis Outcome Quality of life (QOL) Radiation Surgery 



Funding: Department of Neurosurgery and the Hermelin Brain Tumor Center, Henry Ford Health System.

Conflict of Interest: There are no conflicts of interest to declare.


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© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.Departments of Neurosurgery and NeurologyHenry Ford Health SystemDetroitUSA

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