Whole Brain Radiotherapy (WBRT) for Brain Metastases

  • Frédéric DhermainEmail author


WBRT was the historical reference in the management of metastatic patients with brain metastases (BMs) both acting as a palliative tool for symptomatic patients and also by effectively preventing the risk of developing new BMs, including the postoperative setting [1]. To be noted and until the early 2000s, median overall survival (OS) of these patients was usually between 6 and 9 months, and consequently neurocognitive status and quality of life were evaluated with ‘basic’ tools such as the Karnofsky Performance Status (KPS), the MMSE (Mini-Mental Status Exam) or the EORTC QLQ (Quality of Life Questionnaire)-Brain Neurologic (BN-20) module, also due to the lack of time devoted to this clearly ‘palliative’ care.


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© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.Department of Radiation OncologyInstitut Gustave Roussy, University HospitalVillejuifFrance

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