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Brucellar Arthritis

  • Eduardo Gotuzzo Herencia
  • Karen Isabel Vega-Villanueva
Chapter

Abstract

Brucellosis has a long-standing history being first described by Hippocrates, and despite of its ancient history, it has not been possible to control or eradicate it, and it remains endemic in many parts of the world. Fever, low back pain, and arthralgias/arthritis are the classic triad that we will find in florid cases of the disease, although we cannot ignore that it could also be a cause of fever of unknown origin (FUO). Being a systemic disease, one of its main complications is osteoarticular involvement, more specifically brucellar arthritis.

Great progress has occurred in its diagnosis in which ELISA or a molecular technique such as PCR facilitates its rapid detection, and imaging techniques such as nuclear magnetic resonance have become very important for an early diagnosis as well as in patient follow-up. Therapies, however, have not evolved much from the antibiotics developed in the 1950s, and at present, antibiotic regimens used to treat both new cases and relapses in brucellosis are similar.

Keywords

Brucella sp. Arthritis Spondylitis Sacroiliitis Brucella in children Agglutination titers Culture PCR MRI Doxycycline Streptomycin Rifampicin 

Notes

Conflicts of Interest

EMM: None. KVV: None.

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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Eduardo Gotuzzo Herencia
    • 1
  • Karen Isabel Vega-Villanueva
    • 2
  1. 1.Department of Infectious, tropical and dermatological diseasesCayetano Heredia National HospitalLimaPeru
  2. 2.Department of Medicine – Section of RheumatologyCayetano Heredia National HospitalLimaPeru

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