Mitral Regurgitation

  • Madalina Garbi
  • Julien Magne
  • Francesco Maisano
  • Martin Swaans
  • Raluca Dulgheru
  • Patrizio LancellottiEmail author


Mitral regurgitation is the heart valve disease with the highest prevalence and the second most frequently needing intervention. Primary mitral regurgitation is caused by abnormalities of the mitral valve components, whilst secondary mitral regurgitation is caused by abnormalities of the juxtaposed cardiac chambers, the left ventricle and/or the left atrium. Assessment, prognosis and management of mitral regurgitation depend on the primary or secondary nature of the disease. This chapter describes mitral regurgitation pathogenesis, epidemiology, aetiology, physiopathology, clinical presentation, physical examination, diagnosis and treatment.


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Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Madalina Garbi
    • 1
  • Julien Magne
    • 2
    • 3
  • Francesco Maisano
    • 4
  • Martin Swaans
    • 5
  • Raluca Dulgheru
    • 6
  • Patrizio Lancellotti
    • 7
    • 8
    • 9
    Email author
  1. 1.Royal Papworth HospitalCambridgeUK
  2. 2.Service Cardiologie, CHU Limoges, Hôpital DupuytrenLimogesFrance
  3. 3.Faculté de Médecine de Limoges, INSERM 1094LimogesFrance
  4. 4.Professor and Chair of Cardiac Surgery, University Hospital of Zurich, University of ZurichZurichSwitzerland
  5. 5.Department of CardiologySt. Antonius Hospital, koekoekslaan 1NieuwegeinThe Netherlands
  6. 6.GIGA Cardiovascular Sciences Department of CardiologyUniversity of Liège Hospital, CHU Sart Tilman LiègeLiègeBelgium
  7. 7.GIGA Cardiovascular Sciences Department of CardiologyUniversity of Liège Hospital, CHU Sart Tilman LiègeLiègeBelgium
  8. 8.Gruppo Villa Maria Care and Research, Anthea HospitalBariItaly
  9. 9.Department of CardiologyUniversity Hospital Sart Tilman, University of LiègeLiègeBelgium

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