• Helmut Popper
  • Bruno Murer
Part of the Essentials of Diagnostic Pathology book series (ESSENTPATH)


  • The spectrum of bronchiolitis is broad and heterogeneous. In deciphering the potential significance of bronchiolitis, it is useful to distinguish the primary bronchiolitis in which the bronchiolar involvement is the dominant pathologic process from disorders with bronchiolar pathology secondary to other lung diseases. Primary bronchiolar disorders include acute bronchiolitis, constrictive bronchiolitis, follicular bronchiolitis, respiratory bronchiolitis, diffuse panbronchiolitis, mineral dust airway disease, and peribronchiolar metaplasia.

  • Interstitial lung diseases with prominent bronchiolar involvement include smoking-related interstitial diseases, cryptogenic organizing pneumonia, and hypersensitivity pneumonitis. These types of bronchiolitis are considered in other chapters. Finally, bronchiolitis can also be seen in chronic bronchitis, bronchiectasis, and asthma.

Further Reading

  1. Colby TV. Bronchiolitis pathologic considerations. Am J Clin Pathol. 1998;109:101–9.CrossRefGoogle Scholar
  2. Popper H. Chapter 6: Morphology-pathogenesis-etiology. In: Pathology of lung disease. Berlin: Springer; 2017. p. 84–99. Scholar
  3. Rice A, Nicholson AG. The pathologist’s approach to small airways disease. Histopathology. 2009;54:117–33.CrossRefGoogle Scholar
  4. Ryu JH. Classification and approach to bronchiolar diseases. Curr Opin Pulm Med. 2006;12:145–51.CrossRefGoogle Scholar
  5. Ruy JH, Myers JL, Swensen SJ. Bronchiolar disorders. Am J Respir Crit Care Med. 2003;168:1277–92.CrossRefGoogle Scholar
  6. White ES, Tazelaar HD, Lynch JP. Bronchiolar complications of connective tissue diseases. Semin Respir Crit Care Med. 2003;24:543–66.CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Helmut Popper
    • 1
  • Bruno Murer
    • 2
  1. 1.Department of PathologyMedical University GrazGrazAustria
  2. 2.Department of Clinical PathologyOspedale dell’Angelo ASL 3 SerenissimaMestre-VeniceItaly

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