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Reporting of Pancreatico-biliary Cytopathology

  • Abha GoyalEmail author
Chapter
Part of the Essentials in Cytopathology book series (EICP, volume 28)

Abstract

Until recently, there was no standardized reporting system for pancreatico-biliary cytology. In 2014, the Papanicolaou Society of Cytopathology (Pap Society) published guidelines for reporting of pancreatico-biliary cytology. These guidelines were developed by a multidisciplinary group of experts following review of literature and discussion through an interactive Web-based forum and presentation at national and international meetings. The Pap Society reporting scheme includes six diagnostic categories: nondiagnostic, negative, atypical, neoplastic, suspicious for malignancy, and positive. The “neoplastic” category is further subdivided into “neoplastic: benign” and “neoplastic: other.” The premalignant neoplastic mucinous cysts and low-grade neoplasms of the pancreas are categorized as “neoplastic: other.” These categories correlate with the biologic behavior of the various neoplastic and nonneoplastic entities and have been shown to be associated with a risk of malignancy that increases from the negative to the malignant category. These guidelines emphasize a multidisciplinary approach, i.e., incorporating the clinical presentation, the imaging and ultrasound findings, results of cyst fluid biochemistry, and molecular analysis in formulating a cytologic diagnosis. This chapter will discuss the Pap Society nomenclature for pancreatico-biliary cytology and its practical application in daily practice.

Keywords

Papanicolaou Society Reporting Pancreatico-biliary cytology Risk of malignancy Guidelines 

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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of Pathology and Laboratory MedicineWeill-Cornell Medicine, New York Presbyterian HospitalNew YorkUSA

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