Advertisement

The Effect of Heat-Treatment and Bioresorbability of Silicate-Containing Hydroxyapatite

  • Tatyana Panova
  • Olga A. GolovanovaEmail author
Conference paper
  • 101 Downloads
Part of the Lecture Notes in Earth System Sciences book series (LNESS)

Abstract

The possibility of modification of hydroxyapatite of a prototype extracellular liquid synthesized from solution under close physiological conditions by silicate ions was studied. The formation of chemically structured hydroxyapatite with various degrees of substitution of phosphate groups in silicate groups was established by chemical and X-ray diffraction analysis, IR spectroscopy and optical microscopy. It is shown that apatite modified by silicon has an imperfect structure and crystallizes in the nanocrystalline state. It was found that during the experiment an increase in the calcination temperature to 200–1000 °C leads to weight loss. The greatest loss of mass occurs at temperatures in the range of 25–400 °C, which is due to the removal of crystallization and adsorption water and volatile impurities. Three main stages of thermal decomposition of Si-HA are isolated, the final product is a mixture consisting of two phases: Si-HA and β-TKF. The results of the research can be used to study the kinetics of dissolution and the biocompatibility of ceramic materials for medicine, namely for reconstructive surgery, dentistry, and development of drug delivery systems.

Keywords

Hydroxyapatite XRD IR spectroscopy Extracellular fluid Structure Phase composition Degradation Thermal effects Bioresorbability 

References

  1. Bandyopadhyay A, Bernard S, Xue W, Bose S (2006) Calcium phosphate-based resorbable ceramics: influence of MgO, ZnO and SiO2 dopants. J Am Ceram Soc 89:2675–2678CrossRefGoogle Scholar
  2. Berdinskaya MV, Golovanova OA, Zaits AV, Drozdov VI, Leont’eva NN Anthonicheva NV (2014) A physicochemical study of the structure, composition, and properties of hydroxylapatite modified by silicate ions. J Struct Chem 5:954–961CrossRefGoogle Scholar
  3. Chang MC, Кo CC, Douglas WH (2003) Preparation of hydroxyapatite-gelatin nanocomposite. Biomaterials 24:2853–2862CrossRefGoogle Scholar
  4. Golovan AP, Turov VV, Barvinchenko VM, Mishchenko VM, Gorbik PP, Shevchenko YB (2007) Nanostructured composites based on proteins of bone tissue, highly disperse silica and hydroxyapatite. J Khimiya, fizika ta tekhnologiya poverhni 13:309–316Google Scholar
  5. Gomes S, Nedelec J, Jallot E, Sheptyakov D, Renaudin G (2011) Silicon location in silicate-substituted calcium phosphate ceramics determined by neutron diffraction. J Cryst Growth Des 11:4017–4026CrossRefGoogle Scholar
  6. Grubova IY, Ivanova AA, Primak O, Epple M (2014) Osteoinductive coatings based on silicon-substituted hydroxylapatite: physical and chemical properties and in vitro studies. New technologies for creating and using bioceramics in regenerative medicine, pp 154–159Google Scholar
  7. Hench L, Jones D (2007) Biomaterials, artificial organs and tissue engineering. J Technosphere 301Google Scholar
  8. Khlusov IA, Surmeneva MA, Surmenev RA, Ryazantseva NV, Saveleva OE, Ivanova AA, Prokhorenko TS, Tashireva LA, Dvornichenko MV, Pichugin VF (2012) Cell-molecular aspects of immunological compatibility of implants with nanostructured calcium-phosphate coating. J Bull Siberian Med 4:78–85Google Scholar
  9. Marchat D, Zymelka M, Coelho C et al (2013) Accurate characterization of pure silicon-substituted hydroxyapatite powders synthesized in a new deposition pathway. Acta Biomater 9:6992–7004CrossRefGoogle Scholar
  10. Meshkova NP, Severina SE (1979) Workshop on biochemistry. Moscow State University, MoscowGoogle Scholar
  11. Morgan H, Wilson RM, Elliott JC, Dowker SE et al (2000) Preparation and characterisation of monoclinic hydroxyapatite and its precipitated carbonate apatite intermediate. J Biomater 21:617–627CrossRefGoogle Scholar
  12. Murugan R, Ramakrishna S (2005) Crystallografic study of hydroxyapatite bioceramics derived from various sources. J Cryst Growth Des 5:111–116CrossRefGoogle Scholar
  13. Saki M (2009) Biocompatibility study of a hydroxyapatite-alumina and silicon carbide composite scaffold for bone tissue engineering. J Yakhteh 11:55–60Google Scholar
  14. Soin AV, Evdokimov PV, Veresov AG, Putlyaev VI (2007) Synthesis and study of silicon-substituted hydroxyapatites Ca10(PO4), 6–x(SiO4)x(OH). J Altern Energy Ecol 45:130Google Scholar
  15. Solonenko AP, Golovanova OA (2013) Thermal effects in composite materials based on calcium phosphates. Russ J Inorg Chem 1–2:33–38Google Scholar
  16. Solonenko AP, Golovanova OA (2014) Silicate-substituted carbonated hydroxyapatite powders prepared by precipitation from aqueous solutions. Russ J Inorg Chem 59:1228–1236CrossRefGoogle Scholar
  17. Tkhuan LV, Dat DV, Temirkhanova GE (2011) Synthesis and investigation of the morphology of silicon substituted hydroxyapatite, in Sbornik material. IV Vserossiiskoi konferentsii “Nauchnaya initsiativa inostrannykh studentov and aspirantov rossiiskikh vuzov”. pp 346–349 (in Russian)Google Scholar
  18. Wang Y, Zhang S, Zeng X, Cheng K, Qian M, Weng W (2007) In vitro behavior of fluoridated hydroxyapatite coatings inorganic-containing simulated body fluid. J Mater Sci Eng 27:244–250CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.F.M. Dostoevsky State UniversityOmskRussia

Personalised recommendations