Penile Transplantation: The Last Frontier in Penile Reconstruction
Penile allotransplantation, which can be classified as a vascularized composite tissue allotransplantation (VCA), is a new technique pushing the frontiers of reconstructive surgery in an attempt to address the serious shortcomings in the current techniques of penile reconstruction in specifically those patients where there is a complete absence of penile tissue. Several conditions may lead to penile loss, each of which may require a unique approach to ensure a successful outcome. The first successful penis transplantation was performed in 2014, and to date (2018) a total of only four cases have been performed worldwide. All four cases did well with normal or improving erectile function and normal urination. Why not more cases are being attempted is a question that needs to be addressed.
KeywordsPenile transplantation Genital transplantation Allotransplantation Phalloplasty Aphallia Immunosuppression Erectile function Ritual circumcision Genital blast injury Genital trauma Penile cancer Penectomy Vascularised composite tissue allotransplantation VCA
- 1.van der Merwe A, Graewe F, Zuhlke A, Barsdorf NW, Zarrabi AD, Viljoen JT, Ackermann H, Spies PV, Opondo D, Al-Qaoud T, Bezuidenhout K, Nel JD, Bailey B, Moosa MR. Penile allotransplantation for penis amputation following ritual circumcision: a case report with 24 months of follow-up. Lancet. 2017;390:1038–47.CrossRefGoogle Scholar