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Recurrent Bronchiolitis

  • Sevgi Köstel Bal
  • Figen Doğu
Chapter

Abstract

  • The most common infectious agents in combined immunodeficiencies are intracellular pathogens, such as cytomegalovirus, herpes simplex virus, Pneumocystis jirovecii, Salmonella and Cryptosporidium.

  • Immunophenotyping in patients with MHC class II deficiency shows absent or very low HLA-DR expression on B lymphocytes, monocytes or activated T lymphocytes, with reduced CD4+ cell counts leading to an inverted CD4+/CD8+ ratio

Keywords

MHC class II deficiency HLA-DR CD4+/CD8+ ratio Pneumocystis jirovecii 

References

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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Sevgi Köstel Bal
    • 1
  • Figen Doğu
    • 1
  1. 1.Ankara University School of Medicine, Department of Pediatric Allergy and ImmunologyAnkaraTurkey

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