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Anal Cancer pp 85-93 | Cite as

Management of Local-Regional Anal Cancer Recurrence

  • Shilpa S. Murthy
  • Elin R. Sigurdson
Chapter

Abstract

Anal cancer, a rare gastrointestinal disease, accounts for 1–2.5% of gastrointestinal cancers. Primary treatment is chemoradiation. Ten to 30% of patients experience local relapse, and salvage surgery is a second line of treatment for these patients. Wide local excision, abdominoperineal resection, pelvic exenteration with or without sacrectomy, and inguinal node dissection are all surgical options. In this chapter, we review the management and treatment options for patients who are initially treated with chemoradiation and experience local-regional recurrence of the disease.

Keywords

Locoregional failure Recurrent anal cancer Salvage surgery Abdominoperineal resection Pelvic exoneration Inguinal node dissection Surgery for metastatic disease Salvage chemoradiation 

Abbreviations

5-FU

5-Fluorouracil

APR

Abdominoperineal resection

HAART

Highly active antiretroviral therapy

HIV

Human immunodeficiency virus

HPV

Human papillomavirus

MRI

Magnetic resonance imaging

SCC

Squamous cell carcinoma

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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Shilpa S. Murthy
    • 1
  • Elin R. Sigurdson
    • 1
  1. 1.Department of Surgical Oncology, Fox Chase Cancer CenterTemple UniversityPhiladelphiaUSA

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