Drug Delivery Advances for the Regeneration of Aged Skin

  • Daniela Castillo Pérez
  • Matthias M. AitzetmüllerEmail author
  • Philipp Neßbach
  • Dominik Duscher


Due to a permanent shift of the human population towards higher age, also skin aging, its underlying mechanisms and possibilities to reverse these alterations have gained more attention. Although main triggering factors for aging skin degeneration have been identified, mitigating the signs of cutaneous aging is an ongoing scientific challenge. One promising alley of research is drug delivery systems (DDS) for systemic or local administration of regenerative compounds. DDS can enhance the efficacy of regenerative agents while minimizing side effects and enable the specific targeting of certain structures within the integument.


Drug delivery Skin aging Aging Regeneration Rejuvenation Skin barrier 


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Daniela Castillo Pérez
    • 1
  • Matthias M. Aitzetmüller
    • 2
    • 3
    Email author
  • Philipp Neßbach
    • 2
  • Dominik Duscher
    • 4
  1. 1.Biotechnology Research CenterCosta Rica Institute of TechnologyCartagoCosta Rica
  2. 2.Department of Plastic and Hand Surgery, Klinikum Rechts der IsarTechnical University of MunichMunichGermany
  3. 3.Section of Plastic and Reconstructive Surgery, Department of Trauma, Hand and Reconstructive SurgeryWestfaelische Wilhelms, University of MuensterMuensterGermany
  4. 4.Department for Plastic Surgery and Hand Surgery, Division of Experimental Plastic SurgeryTechnical University of MunichMunichGermany

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