Integration of “Omic” Approaches to Unravel the Heavy Metal Tolerance in Plants

  • Tanveer Bilal Pirzadah
  • Bisma Malik
  • Khalid Rehman Hakeem


Recent adverse climatic changes have limited crop productivity, which in turn causes food crises throughout the globe, but this is more concerning for developing countries. Interest for practical genomics as well as proteomics is currently widespread to understand the mechanism(s) of stress tolerance. The information gained through the said methods would facilitate the nutritional management and metabolic and genetic improvement of plants of our interest. Genomic and proteomic studies of control and stressed plants have empowered the recognizable proof of various traits and proteins that assume vital part in granting stress resistance to plants. Therefore, identification of “stress-responsive” protein(s)/gene(s) and utilization of thus obtained data provide a great chance to reduce effects of any particular or combined stress on plant. On the other hand, it is also necessary to investigate the cross talk between key stress reaction pathways/components in order to better understand the regulation of protection mechanism. This review provides a critical and extensive analysis of the proteomic profiling of plants in reply to heavy metal stress and highlights key techniques being employed for accomplishing ever-desired success. It also revealed an account of proteins identified to impart resistance under different abiotic stresses in plants. In addition, we present the role of functional genomics and various bioinformatics tools to understand the proteome maps of heavy metal-stressed plants.


Heavy metal stress Proteomics Functional genomics Bioinformatics 


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© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Tanveer Bilal Pirzadah
    • 1
    • 2
  • Bisma Malik
    • 1
  • Khalid Rehman Hakeem
    • 3
    • 4
  1. 1.Department of BioresourcesUniversity of KashmirSrinagarIndia
  2. 2.Department of Bioresources, Amar Singh CollegeCluster UniversitySrinagarIndia
  3. 3.Department of Biological SciencesKing Abdulaziz UniversityJeddahSaudi Arabia
  4. 4.Princess Dr. Najla Bint Saud Al-Saud Center for Excellence Research in BiotechnologyKing Abdulaziz UniversityJeddahSaudi Arabia

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