DNA Origami Words and Rewriting Systems

  • James Garrett
  • Nataša Jonoska
  • Hwee KimEmail author
  • Masahico Saito
Conference paper
Part of the Lecture Notes in Computer Science book series (LNCS, volume 11493)


We classify rectangular DNA origami structures according to their scaffold and staples organization by associating a graphical representation to each scaffold folding. Inspired by well studied Temperley-Lieb algebra, we identify basic modules that form the structures. The graphical description is obtained by ‘gluing’ basic modules one on top of the other. To each module we associate a symbol such that gluing of molecules corresponds to concatenating the associated symbols. Every word corresponds to a graphical representation of a DNA origami structure. A set of rewriting rules defines equivalent words that correspond to the same graphical structure. We propose two different types of basic module structures and corresponding rewriting rules. For each type, we provide the number of all possible structures through the number of equivalence classes of words. We also give a polynomial time algorithm that computes the shortest word for each equivalence class.



This work is partially supported by NIH R01GM109459, and by NSF’s CCF-1526485, DMS-1800443 and DMS-1764366.


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • James Garrett
    • 1
  • Nataša Jonoska
    • 1
  • Hwee Kim
    • 1
    Email author
  • Masahico Saito
    • 1
  1. 1.Department of Mathematics and StatisticsUniversity of South FloridaTampaUSA

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