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Gastrointestinal Lymphomas

  • Alma Aslan
  • Serkan Akın
  • Taner Babacan
  • Evren Özdemir
Chapter

Abstract

Primary gastrointestinal (GI) lymphomas constitute 1–4% of all gastrointestinal malignancies, and 90% are of B-cell type. The most commonly involved sites are as follows: stomach (60–75%), small intestine (9%), ileocecal region (7%), and colorectal region (<1%). Certain histological subtypes of lymphomas may preferentially involve specific sites in the gastrointestinal tract. There are several known risk factors for the development of primary GI lymphoma. Pretreatment work-up and tissue biopsy are necessary for definitive diagnosis and evaluation of the extent of the disease. There is limited consensus on the staging system of primary GI lymphoma, with three staging systems in use: Ann-Arbor staging with Musshoff modification, Lugano staging system, and Paris staging system. The treatment depends upon the patient’s clinical condition, histological subtype, and stage of the disease and may range from observation to stem cell transplantation. This chapter will focus on the most common primary GI lymphomas of the stomach, small intestine, and colon and extranodal involvement of the GI tract by systemic lymphomas. Epidemiology, etiology, risk factors, diagnostic procedures, staging, treatment, and follow-up of GI lymphomas will be discussed.

Keywords

Lymphoma Non-Hodgkin’s lymphoma Gastrointestinal system Gastrointestinal tract Gastric lymphoma Intestinal lymphoma Extranodal lymphoma 

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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Alma Aslan
    • 1
  • Serkan Akın
    • 1
  • Taner Babacan
    • 1
  • Evren Özdemir
    • 1
  1. 1.Department of Medical OncologyHacettepe University Institute of CancerSıhhiyeTurkey

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