46-Year-Old with Psoriasis and Chronic Hepatitis C

  • Kevin K. Wu
  • Michael P. Lee
  • Jashin J. Wu
Part of the Clinical Cases in Dermatology book series (CLIDADE)


Hepatitis C (HCV) is a viral infection that is associated with a higher risk of psoriasis. Treatment of psoriasis in patients with comorbid HCV is challenging because many psoriasis therapies are hepatotoxic or immunosuppressive. First-line treatments for psoriasis patients with concomitant HCV include phototherapy, topical therapies, and apremilast. Methotrexate should be avoided due to potential hepatotoxicity.


Hepatitis C Psoriasis Hepatotoxic Phototherapy TNF inhibitors Apremilast Methotrexate 


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Kevin K. Wu
    • 1
  • Michael P. Lee
    • 2
  • Jashin J. Wu
    • 3
  1. 1.Frank H. Netter MD School of Medicine at Quinnipiac UniversityNorth HavenUSA
  2. 2.Eastern Virginia Medical SchoolNorfolkUSA
  3. 3.Founder and CEODermatology Research and Education FoundationIrvineUSA

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