Advertisement

Diagnosis and Treatment

  • Jan Dirk Blom
Chapter

Abstract

How should Alice in Wonderland syndrome be diagnosed? How should it be treated? For numerous other medical conditions, diagnostic criteria are available from scientific organisations such as the World Health Organization, the American Psychiatric Association, the International League Against Epilepsy and so on. In addition, these organisations may issue evidence-based guidelines which stipulate how disorders should preferably be treated. However, for Alice in Wonderland syndrome, no such diagnostic criteria and therapeutic algorithms are available. As you probably have guessed, that is because the syndrome has until now hardly been investigated. As a consequence, Alice in Wonderland syndrome is perhaps the poster child for orphan diseases: a condition ‘forgotten’ by the powers that be and, therefore, playing no role whatsoever in the canon of medicine.

References

  1. 1.
    [Anonymous] (1956) The “Alice in Wonderland” syndrome: relation to migraine. Based on an article by Todd J (1955) Canad Med Assn J 73: 701. In: Abbott Laboratories (ed) What’s new. Special Christmas Edition 1956. Abbott Laboratories, North Chicago, pp 22–24Google Scholar
  2. 2.
    Todd J (1955) The syndrome of Alice in Wonderland. Can Med Assoc J 73:701–704PubMedPubMedCentralGoogle Scholar
  3. 3.
    Lippman CW (1952) Certain hallucinations peculiar to migraine. J Nerv Ment Dis 116:346–351CrossRefGoogle Scholar
  4. 4.
    Todd J, Collins AD, Martin FRR, Dewhurst KE (1962) Mental symptoms due to insulinomata. Report on two cases. Br Med J 2(5308):828–831CrossRefGoogle Scholar
  5. 5.
    World Health Organisation (1992) The international classification of diseases, 10th revision. World Health Organisation, GenevaGoogle Scholar
  6. 6.
    American Psychiatric Association (2013) Diagnostic and statistical manual of mental disorders, 5th edn. American Psychiatric Association, WashingtonCrossRefGoogle Scholar
  7. 7.
    Morehead DB (1997) Exacerbation of hallucinogen-persisting perception disorder with risperidone. J Clin Psychopharmacol 17:327–328CrossRefGoogle Scholar
  8. 8.
    Blom JD, Looijestijn J, Goekoop R, Diederen KMJ, Rijkaart A-M, Slotema CW, Sommer IEC (2011) Treatment of Alice in Wonderland syndrome and verbal auditory hallucinations using repetitive transcranial magnetic stimulation. A case report with fMRI findings. Psychopathology 44:337–344CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Jan Dirk Blom
    • 1
    • 2
    • 3
  1. 1.Parnassia Psychiatric InstituteThe HagueThe Netherlands
  2. 2.Leiden UniversityLeidenThe Netherlands
  3. 3.University of GroningenGroningenThe Netherlands

Personalised recommendations