Advertisement

Neuroblastoma pp 313-325 | Cite as

Surgical Techniques

  • James A. SaltsmanIII
  • Nicole J. Croteau
  • Michael P. LaQuagliaEmail author
Chapter

Abstract

Surgery is an integral part of the diagnosis and management of neuroblastoma. Although molecular and histologic factors greatly influence patient outcomes, appropriate surgical technique in these patients must take into account age and the complexities inherent in the specific anatomic locations where the tumors arise. In this chapter, we briefly review patient risk stratification schemes set forth by the International Neuroblastoma Risk Group and the International Neuroblastoma Staging System, followed by a description of appropriate surgical techniques for tumor debulking and resection in cervical, thoracic, abdominal, and pelvic locations. Preoperative and anesthesia considerations are also summarized.

Keywords

Neuroblastoma Pediatric surgery Risk stratification Cervical incision Trap-door incision Clamshell incision Vascular encasement Adrenal tumor Mediastinal tumor Retroperitoneal incision 

References

  1. 1.
    Gross RE, Piotti E. The surgery of infancy and childhood: its principles and techniques. Philadelphia: Saunders; 1953, xxiv, 1000pGoogle Scholar
  2. 2.
    Koop CE, Kiesewetter WB, Horn RC. Neuroblastoma in childhood; survival after major surgical insult to the tumor. Surgery. 1955;38(1):272–8.PubMedGoogle Scholar
  3. 3.
    Harrison J, Myers M, Rowen M, Vermund H. Results of combination chemotherapy, surgery, and radiotherapy in children with neuroblastoma. Cancer. 1974;34(3):485–90.CrossRefGoogle Scholar
  4. 4.
    Hollmann G, Lampert F. Carcinochemotherapy in pediatric surgery (author’s transl). Langenbecks Arch Chir. 1975;339:95–8.CrossRefGoogle Scholar
  5. 5.
    Stephen CR. Anesthesia for adrenal surgery. Urol Clin North Am. 1977;4:319–26.PubMedGoogle Scholar
  6. 6.
    Tsunooka H. Progress in diagnostic methods in pediatric surgery. Geka Chiryo. 1972;26(2):140–60.PubMedGoogle Scholar
  7. 7.
    Nitschke R, Smith EI, Shochat S, Altshuler G, Travers H, Shuster JJ, et al. Localized neuroblastoma treated by surgery: a Pediatric Oncology Group Study. J Clin Oncol. 1988;6(8):1271–9.CrossRefGoogle Scholar
  8. 8.
    Brodeur GM, Pritchard J, Berthold F, Carlsen NL, Castel V, Castelberry RP, et al. Revisions of the international criteria for neuroblastoma diagnosis, staging, and response to treatment. J Clin Oncol. 1993;11(8):1466–77.CrossRefGoogle Scholar
  9. 9.
    Cohn SL, Pearson AD, London WB, Monclair T, Ambros PF, Brodeur GM, et al. The International Neuroblastoma Risk Group (INRG) classification system: an INRG Task Force report. J Clin Oncol. 2009;27(2):289–97.CrossRefGoogle Scholar
  10. 10.
    Monclair T, Brodeur GM, Ambros PF, Brisse HJ, Cecchetto G, Holmes K, et al. The International Neuroblastoma Risk Group (INRG) staging system: an INRG Task Force report. J Clin Oncol. 2009;27(2):298–303.CrossRefGoogle Scholar
  11. 11.
    Monclair T, Mosseri V, Cecchetto G, De Bernardi B, Michon J, Holmes K. Influence of image-defined risk factors on the outcome of patients with localised neuroblastoma. A report from the LNESG1 study of the European International Society of Paediatric Oncology Neuroblastoma Group. Pediatr Blood Cancer. 2015;62(9):1536–42.CrossRefGoogle Scholar
  12. 12.
    Holmes K, Sarnacki S, Poetschger U, Monclair T, Cecchetto G, Buffa P, et al., editors. Influence of surgical excision on survival of patients with high-risk neuroblastoma, report from study 1 of SIOP Europe (SIOPEN) [abstract PL012]. In: Advances in neuroblastoma research: ANR 2014 conference proceedings, Cologne, Germany. 2014.Google Scholar
  13. 13.
    von Allmen D, Davidoff AM, London WB, Van Ryn C, Haas-Kogan DA, Kreissman SG, et al. Impact of extent of resection on local control and survival in patients from the COG A3973 study with high-risk neuroblastoma. J Clin Oncol. 2017;35(2):208–16.CrossRefGoogle Scholar
  14. 14.
    Kohler JA, Rubie H, Castel V, Beiske K, Holmes K, Gambini C, et al. Treatment of children over the age of one year with unresectable localised neuroblastoma without MYCN amplification: results of the SIOPEN study. Eur J Cancer. 2013;49(17):3671–9.CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • James A. SaltsmanIII
    • 1
  • Nicole J. Croteau
    • 1
  • Michael P. LaQuaglia
    • 1
    Email author
  1. 1.Department of SurgeryMemorial Sloan Kettering Cancer CenterNew YorkUSA

Personalised recommendations