Nasal Congestion Since Childhood

  • Charmi Patel
  • Punita PondaEmail author

Practical Points

  • Allergic rhinitis and allergic asthma are common primary indications for allergen immunotherapy

  • Immunological changes from immunotherapy include a decrease in mast cell and basophil degranulation, early increase and later decrease in allergen-specific IgE levels, increase in allergen-specific IgG, IgG4 and IgA levels, increase in regulatory T cells with an increase in IL-10 and TGF-β, and an immunological skewing from Th2 to Th1

  • Cat, dust mites, ragweed and grass extracts are the only standardized environmental allergen extracts in the United States


Allergic rhino-conjunctivitis Allergic rhinitis Allergic asthma Allergen immunotherapy 


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Division of Allergy and ImmunologyDepartment of Medicine, Albany Medical Center, Albany Medical CollegeAlbanyUSA
  2. 2.Division of Allergy and Immunology, Cohen Children’s Hospital of New YorkDonald and Barbara Zucker School of Medicine at Hofstra/NorthwellGreat NeckUSA

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