Advertisement

Hypotension and Erythema During Anesthesia

  • Silviya Mihaylova Novakova
  • Ivan Petkov Novakov
  • Manuela Dimitrova Yoncheva
Chapter

Practical Points

  • Hypersensitivity reactions during anesthesia can be life-threatening

  • In the absence of appropriate allergologist assessment and diagnosis, a subsequent re-exposure can result in serious consequences

  • Serum tryptase level measured between 1 and 4 h after the reaction and skin prick test 4 to 6 weeks after the attack are confirmatory for an anaphylactic reaction

Keywords

Drug-induced hypersensitivity reaction Neuromuscular blocking agents Anaphylaxis 

References

  1. 1.
    International drug monitoring: the role of national centres. Report of a WHO meeting. World Health Organ Tech Rep Ser. 1972;498:1–25.Google Scholar
  2. 2.
    Demoly P, Adkinson NF, Brockow K, Castells M, Chiriac AM, Greenberger PA, Khan DA, Lang DM, Park HS, Pichler W, Sanchez-Borges M, Shiohara T, Thong BY. International consensus on drug allergy. Allergy. 2014;69(4):420–37.CrossRefGoogle Scholar
  3. 3.
    Mertes PM, Laxenaire MC, Lienhart A, Aberer W, Ring J, Pichler WJ, Demoly P. Reducing the risk of anaphylaxis during anaesthesia: guidelines for clinical practice. J Investig Allergol Clin Immunol. 2005;15(2):91–101.PubMedGoogle Scholar
  4. 4.
    Mertes PM, Demoly P, Malinovsky JM. Hypersensitivity reactions in the anesthesia setting/allergic reactions to anesthetics. Curr Opin Allergy Clin Immunol. 2012;12(4):361–8.CrossRefGoogle Scholar
  5. 5.
    Harper NJ, Dixon T, Dugue P, Edgar DM, Fay A, Gooi HC, Herriot R, Hopkins P, Hunter JM, Mirakian R, Pumphrey RS, Seneviratne SL, Walls AF, Williams P, Wildsmith JA, Wood P, Nasser AS, Powell RK, Mirakhur R, Soar J. Suspected anaphylactic reactions associated with anaesthesia. Anaesthesia. 2009;64(2):199–211.CrossRefGoogle Scholar
  6. 6.
    Hsu Blatman KS, Hepner DL. Current knowledge and management of hypersensitivity to perioperative drugs and radiocontrast media. J Allergy Clin Immunol Pract. 2017;5(3):587–92.CrossRefGoogle Scholar
  7. 7.
    Brockow K, Garvey LH, Aberer W, Atanaskovic-Markovic M, Barbaud A, Bilo MB, Bircher A, Blanca M, Bonadonna B, Campi P, Castro E, Cernadas JR, Chiriac AM, Demoly P, Grosber M, Gooi J, Lombardo C, Mertes PM, Mosbech H, Nasser S, Pagani M, Ring J, Romano A, Scherer K, Schnyder B, Testi S, Torres M, Trautmann A, Terreehorst I. Skin test concentrations for systemically administered drugs -- an ENDA/EAACI Drug Allergy Interest Group position paper. Allergy. 2013;68(6):702–12.CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Silviya Mihaylova Novakova
    • 1
  • Ivan Petkov Novakov
    • 2
  • Manuela Dimitrova Yoncheva
    • 3
  1. 1.Allergy Unit, Internal Consulting DepartmentUniversity Hospital “St. George”PlovdivBulgaria
  2. 2.Department of Special SurgeryMedical UniversityPlovdivBulgaria
  3. 3.Internal Consulting DepartmentUniversity Hospital “St. George”PlovdivBulgaria

Personalised recommendations