Recurrent Angioedema of the Eyes and Lips

  • Eva Rebelo Gomes
  • Carmo AbreuEmail author

Practical Points

  • All patients with a suspicion of anaphylaxis attack should be screened for systemic mastocytosis using baseline serum tryptase levels

  • Cutaneous symptoms are the most common manifestation of anaphylaxis while hypotension and shock are less commonly present in pediatric patients

  • Food allergy is the most common cause of anaphylaxis in children

  • A “reaction diary” is a useful tool to identify trigger(s) of the so-called idiopathic anaphylactic reaction

  • History of asthma along with a previous episode of anaphylaxis are strong predictors of future life threatening anaphylactic reaction


Nonsteroidal anti-inflammatory drug NSAID-induced urticaria/angioedema Single-NSAID-induced urticaria/angioedema or anaphylaxis NSAID-exacerbated respiratory disease NSAID-exacerbated cutaneous disease 


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Basic and Clinical Immunology Unit, Laboratory of Immunology, Faculty of MedicineUniversity of PortoPortoPortugal
  2. 2.Centro Hospitalar do PortoPortoPortugal

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