Muscle and Myofascial Pain

  • Rene Przkora
  • Pavel Balduyeu
  • Andrea Trescot


Myofascial pain syndrome (MPS) is a common pain condition and one of a spectrum of soft tissue pain syndromes (Mense and Gerwin, Muscle pain: understanding the mechanisms. Springer, New York, 2010). Patients can demonstrate pain in one or more body regions associated with referred pain to a site not associated with the pain source. Taut muscle bands and especially myofascial trigger points (MTrPs) are the key components of the diagnosis, which is mostly clinical. MPS can be acute or chronic and can be associated with additional pain syndromes such as cervical facet joint syndrome and headaches. An excessive release of acetylcholine (ACh) plays a role in the pathophysiology, triggering more muscle spasms and the release of biologically active molecules, leading to peripheral and central sensitization. Therapy is usually multimodal with physical modalities including stretching exercises and trigger point injection therapy.


Myofascial pain syndrome MPS Fibromyalgia Trigger point Taut bands Trigger point injection Myofascial release Myalgia 


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Rene Przkora
    • 1
  • Pavel Balduyeu
    • 1
  • Andrea Trescot
    • 2
  1. 1.Department of AnesthesiologyCollege of Medicine, University of  FloridaGainesvilleUSA
  2. 2.Pain and Headache CenterEagle RiverUSA

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