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Maternal Use of Other Psychoactive Drugs and Infant Congenital Malformations

  • Bengt Källén
Chapter

Abstract

The use of methylphenidate for ADHD appears to carry little risk for congenital malformations but more adequate studies are needed. There seems to be little concern about a teratogenic effect of drugs for Parkinsonism, parasymphathomimetic drugs, or drugs for vertigo. Practically no information exists on drugs for dementia or ALS. Nicotine replacement therapy (NRT) may not cause malformations but more data are needed. Other drugs used for smoking cessations have so far not demonstrated teratogenicity. Only little information is available on the use of disulfiram and other drugs for alcohol abuse. Methadone used for opioid addiction may increase the malformation risk while buprenorphine seems to be less risky even though findings vary. Further information is needed but a possible risk must be weighed against the risk of untreated drug abuse.

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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Bengt Källén
    • 1
  1. 1.Tornblad Institute for Comparative EmbryologyLund UniversityLundSweden

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