Wolff-Parkinson-White Syndrome

  • Tam Dan N. Pham
  • Mark E. AlexanderEmail author


Wolff-Parkinson-White (WPW) syndrome is a ventricular pre-excitation syndrome affecting approximately 1–3 in 1000 individuals and carries a low, but clinically important, risk of sudden cardiac death. The clinical presentation can vary from asymptomatic WPW to cardiac arrest as the sentinel event. Practice guidelines have been developed for the management of patients with asymptomatic WPW. These guidelines include noninvasive and invasive testing and have ascribed an important role to exercise testing.


Wolff-Parkinson-White syndrome Sudden cardiac death Exercise testing Electrocardiogram Anatomic risk Electrophysiologic risk 


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© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of CardiologyBoston Children’s HospitalBostonUSA
  2. 2.Department of PediatricsHarvard Medical SchoolBostonUSA
  3. 3.Exercise Physiology, Arrhythmia Service, Department of CardiologyBoston Children’s HospitalBostonUSA

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