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Cullen corylifolium (L.) Medicus (Fabaceae/Leguminosae)

(Syns.: C. corylifolius (L.) Medik; Lotodes corylifolia (L.) Kuntze; Psoralea corylifolia L.; P. patersoniae Schonl.; Trifolium unifolium Forssk)
  • Shahid AkbarEmail author
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Abstract

An annual plant found throughout plains of India, especially in the semiarid regions of Rajasthan, Punjab, and Uttar Pradesh, and Iran. The seeds are considered lenitive, fragrant, stimulant and aphrodisiac, and are recommended in the treatment of leprosy, and other chronic skin diseases caused by a vitiated state of blood. In Unani medicine, seeds are classified as blood purifier, anthelmintic, carminative, laxative and to tonify stomach. Due to its blood purifying properties, it is used in skin diseases, such as leprosy, leucoderma, eczema and itching. However, the seeds are required to be used after purification by soaking them in ginger water for a week. In China, ripe fruits are known as Buguzhi, Heiguzi and Poguzhi, and described as acrid and bitter in taste, warm in property, and their actions are kidney-tonyfying, “Yang (vital function)-invigorative,” “stomach and spleen-warming” and antidiarrheal. Mature, dried fruits are officially listed in the Pharmacopoeia of the Peoples’ Republic of China of 2000 (vol II) for the treatment of enuresis, urinary frequency (pollakiuria), waist and knee psychalgia and kidney weakness. The herb is mainly used in China to treat impotence due to “kidney” asthenia, premature ejaculation, nocturnal emissions, enuresis, backache and knee pain, and pollakiuria; externally, it is used for vitiligo, callus, psoriasis, and alopecia. A number of chemical compounds including psoralen, isopsoralen, psoralidin, bakuchiol, bakuchalcone, bavachinin, flavones, volatile oils, and lipids have been reported from different parts of the plant. Aqueous seed extract significantly improved hyperglycemia and glucose tolerance, and increased serum insulin levels in diabetic mice; also significantly reduced body weight, blood glucose levels, improved glucose tolerance and insulin-sensitivity in high fat diet-induced nonalcoholic fatty liver in mice. Inhibition of oxidative stress, and inhibition of α-glucosidase activity by psoralidin, coryfolin, and daidzein may contribute to the antidiabetic activity.

Keywords

Babchi Bakuchi Bokoshi Buguzhi Bukchi Lata-kasturi Loelab el abid Psoraléa Trébol hediondo Waghchi 

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Authors and Affiliations

  1. 1.StocktonUSA

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