Cardiospermum halicacabum L. (Sapindaceae)

  • Shahid AkbarEmail author


A climbing herbaceous, more or less hairy plant (vine) that is a native of Central and South America, but also found in tropical and subtropical Asia and Africa. In Unani medicine, it is described as aphrodisiac and fattening of the body. Aerial parts are diuretic, stomachic, laxative, alterative and rubefacient. Root and leaves are used as decoction for rheumatism, nervous diseases, piles, chronic bronchitis, phthisis and for amenorrhea. Fried leaves are applied to pubis to improve menstrual flow in amenorrhea. Plant juice is dropped into ear for earache and discharge from the meatus. Its non-edible oil is used as insect repellent. Leaves largely contain tannins, saponins and traces of alkaloids. Apigenin, luteolin, and apigenin-7-O-glucoside were identified as the predominant constituents of aerial parts and seeds from Italy. Cardiospermin, a cyanogenic glucoside isolated from root is suggested to be responsible for its anxiolytic activity. Aqueous leaf extract significantly increased sperm count, sperm motility, and serum testosterone level in rats. Anti-inflammatory activity of ethanol extract of aerial parts has been ascribed to the presence of rutin, and berberine, an isoquinoline alkaloid, has been identified as a competitive inhibitor of phospholipase A2. Luteolin-7-O-glucuronide, apigenin-7-O-glucuronide and chrysoeriol have also been identified as anti-inflammatory compounds. Topical application of hexane, ethyl acetate, benzene, chloroform and methanol extracts offered a safe protection against mosquito bites.


Alfombrilla Balãozinho Ballonrebe Dominicani Hubbul-qilqil Kanphuti Kapotavalli Laftaf Tao ti ling Winter cherry 


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© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.StocktonUSA

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