Briefly Summarizing Our Understanding of Vibrio cholerae and the Disease Cholera
Vibrio cholerae is a naturally existing aquatic bacteria that lives in association with the chitinous exoskeletons of crustaceans including copepods. Cholera is an infectious disease of humans which is caused by ingesting those strains of the bacteria Vibrio cholerae that carry both of two disease related factors, a toxin gene coded by the bacteriophage CTXΦ which produces the cholera toxin, and the toxin-coregulated pilus which both facilitates attachment of the bacteria to host cells and also serves as the CTXΦ receptor. Cholera is considered a waterborne infection, with the primary route of infection being ingestion of fecally contaminated water and secondary transmission being caused by ingesting fecally contaminated food. Development of mathematical modeling frameworks may help to provide an essential lead time for strengthening intervention efforts to either prevent or ameliorate outbreaks of cholera in regions where the disease is endemic.
KeywordsCholera Vibrio disease Vibrio cholerae
Compliance with Ethical Standards
Conflict of Interest
Christon J. Hurst declares that he has no conflict of interest.
This article does not contain any studies with human participants or animals.
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