Briefly Summarizing Our Understanding of Vibrio cholerae and the Disease Cholera

  • Christon J. Hurst
Part of the Advances in Environmental Microbiology book series (AEM, volume 7)


Vibrio cholerae is a naturally existing aquatic bacteria that lives in association with the chitinous exoskeletons of crustaceans including copepods. Cholera is an infectious disease of humans which is caused by ingesting those strains of the bacteria Vibrio cholerae that carry both of two disease related factors, a toxin gene coded by the bacteriophage CTXΦ which produces the cholera toxin, and the toxin-coregulated pilus which both facilitates attachment of the bacteria to host cells and also serves as the CTXΦ receptor. Cholera is considered a waterborne infection, with the primary route of infection being ingestion of fecally contaminated water and secondary transmission being caused by ingesting fecally contaminated food. Development of mathematical modeling frameworks may help to provide an essential lead time for strengthening intervention efforts to either prevent or ameliorate outbreaks of cholera in regions where the disease is endemic.


Cholera Vibrio disease Vibrio cholerae 


Compliance with Ethical Standards

Conflict of Interest

Christon J. Hurst declares that he has no conflict of interest.

Ethical Approval

This article does not contain any studies with human participants or animals.


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Christon J. Hurst
    • 1
    • 2
  1. 1.1814 Woodpine Lane, CincinnatiUSA
  2. 2.Universidad del ValleCaliColombia

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