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Non-small Cell Lung Cancer

  • Apichat TantraworasinEmail author
  • Sarawut Kongkarnka
  • Nirush Lertprasertsuke
  • Yutthaphan Wannasopha
  • Juntima Euathrongchit
  • Thatthan Suksombooncharoen
  • Somcharoen Saeteng
  • Sophon Siwachat
  • Busayamas Chewaskulyong
Chapter

Abstract

Non-small cell lung cancer (NSCLC) is most common cause of cancer death in the world. Early detection, diagnosis and treatments are the essential strategies for increased overall survival of patients. Recently, staging of NSCLC is updated to 8th edition of TNM staging for NSCLC issued by the IASLC which affects to overall survival and treatment methods. This chapter include the incidence and risk factors of lung cancer, screening for lung cancer, diagnostic investigation, pathology, stage, and current treatment modalities in each stage of disease. There are many issues in term of multimodality treatments including surgery, radiotherapy, chemotherapy, targeted therapy and immunotherapy.

Keywords

NSCLC Diagnosis Stage Pathology Treatment modalities 

Abbreviations

AATS

American Association for Thoracic Surgery

ACCP

American College of Chest Physicians

ACS

American Cancer Society

ALK

Anaplastic Lymphoma Kinase

ASCO

American Society of Clinical Oncology

BSC

Best Supportive Care

CCRT

Concurrent Chemoradiotherapy

CI

Confidence Interval

CMS

Centers for Medicare & Medicaid Services

COPD

Chronic Obstructive Pulmonary Disease

DFS

Disease-Free Survival

EBUS-NA

Endobronchial Ultrasound Needle Aspiration

EGFR

Epidermal Growth Factor Receptor

ESMO

European Society for Medical Oncology

FEV1

Forced Expiratory Volume in 1 second

IASLC

International Association Study of Lung Cancer

IV

Intravenous

LEC

Large Cell Carcinoma

LN

Lymph Node

LOS

Length of Hospital Stay

L-SND

Lobe-Specific Node Dissection

LUL

Left Upper Lobe

MLN

Mediastinal Lymph Node

MS

Median Survival

NCCN

National Comprehensive Cancer Network

NSCLC

Non-small Cell Lung Cancer

OS

Overall Survival

PFS

Progression-Free Survival

QOL

Quality of Life

RCT

Randomized Controlled Trial

RML

Right Middle Lobe

RR

Response Rate

RT

Radiotherapy

RUL

Right Upper Lobe

SABR

Stereotactic Ablative Radiotherapy

SBRT

Stereotactic Body Radiotherapy

SCC

Small Cell Carcinoma

SCRT

Sequential Chemoradiotherapy

SLND

Systematic Lymph Node Dissection

SLNS

Systematic Lymph Node Sampling

SQCC

Squamous Cell Carcinoma

TBNA

Transbronchial Needle Aspiration

TKI

Tyrosine Kinase Inhibitor

TTNA

Transthoracic Needle Aspiration

USPSTF

US Preventive Services Task Force

VATS

Video-assisted Thoracoscopic Surgery

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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Apichat Tantraworasin
    • 1
    Email author
  • Sarawut Kongkarnka
    • 2
  • Nirush Lertprasertsuke
    • 2
  • Yutthaphan Wannasopha
    • 3
  • Juntima Euathrongchit
    • 3
  • Thatthan Suksombooncharoen
    • 4
  • Somcharoen Saeteng
    • 1
  • Sophon Siwachat
    • 1
  • Busayamas Chewaskulyong
    • 4
  1. 1.Department of Surgery, Faculty of MedicineChiang Mai UniversityChiang MaiThailand
  2. 2.Department of Pathology, Faculty of MedicineChiang Mai UniversityChiang MaiThailand
  3. 3.Department of Radiology, Faculty of MedicineChiang Mai UniversityChiang MaiThailand
  4. 4.Department of Internal Medicine, Faculty of MedicineChiang Mai UniversityChiang MaiThailand

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