Bone Sarcomas

  • Gislaine Fernandes Silva
  • Daiane Pereira Guimarães
  • Hakaru Tadokoro
  • Ramon Andrade De MelloEmail author


Bone sarcomas are primary malignant tumors of osteoid producing cells adjacent to growth plates, which arise more frequently in long bones (Clark J, Rocques PJ, Crew AJ et al: Nat Genet 7:502–508, 1994). Unlike soft tissue sarcomas, which have a wide variety of histological subtypes, bone sarcomas have only three distinct categories: chondrosarcoma, Ewing’s sarcoma and osteosarcoma. Bone sarcomas are more common in children and young adults, with some exceptions in later years. The management of bone sarcomas varies considerably, according to histology, degree and stage (Devita H: Rosemberg’s cancer: principles & practice of oncology. In: VT DV Jr, Lawewnce TS, Rosemberg SA (eds) Chapter 121 with 404 contributing authors, 10th edn. LWW, New York, 2014).


Bone sarcoma Chemotherapy Radiotherapy 


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Gislaine Fernandes Silva
    • 1
  • Daiane Pereira Guimarães
    • 2
  • Hakaru Tadokoro
    • 3
  • Ramon Andrade De Mello
    • 4
    • 5
    Email author
  1. 1.Department of Medical OncologyFederal University of São PauloSão PauloBrazil
  2. 2.Clinical Oncology Medical ProgramFederal University of São Paulo – UNIFESPSão PauloBrazil
  3. 3.Division of Medical Oncology, Escola Paulista de MedicinaFederal University of São PauloSão PauloBrazil
  4. 4.Division of Medical OncologyFederal University of São Paulo (UNIFESP) & Hospital Israelita Albert EinsteinSão PauloBrazil
  5. 5.Department of Biomedical Sciences and MedicineUniversity of AlgarveFaroPortugal

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