Analysis of an Impact of Hemodynamic Parameters in Relation to Variable Morphometric Features of the Middle Cerebral Artery (MCA)
The article-related research work aimed to investigate the effect of the morphometric features of the middle cerebral artery (MCA) on values of hemodynamic parameters present on the artery wall. The research-related tests were performed using the ANSYS® CFX software programme. The objective of the tests involved the development of a parametric model representing the morphometric features of a vessel. The model was based on geometric models of middle cerebral arteries (MCAs) obtained on the basis of angiotomography of patients. Morphometric features subjected to analysis included the radius of the artery inlet and that of the outlet as well as the angle of bifurcation.
Information about values of artery radiuses was necessary to determine the angle of bifurcation. Test simulations involved the use of information about blood flow velocity obtained using a transcranial Doppler ultrasound examination with transcranial colour-coded duplex sonography (TCCS) of a given patient. Hemodynamic parameters subjected to analysis included pressure and wall shear stress (WSS). The simulation results enabled the correlation of the MCA morphometric features with blood flow hemodynamic parameters and revealed the mutual influence of the aforesaid factors.
KeywordsComputational Fluid Dynamics (CFD) Blood flow Artery CT Murray’s law Velocity of blood
The study was supported by the research grant StrategMed 2/269760/1/NCBR/2015 of the National Centre for Research and Development (NCBR).
- 6.Melka, B., Gracka, M., Adamczyk, W., Rojczyk, M., Golda, A., Nowak, A.J., Białecki, R.A., Ostrowski, Z.: Multiphase simulation of blood flow within main thoracic arteries of 8-year-old child with coarctation of the aorta. In: Heat and Mass Transfer (2017). https://doi.org/10.1007/s00231-017-2136-yCrossRefGoogle Scholar
- 7.Murray, C.D.: The physiological principle of minimum work. I. The vascular system and the cost of blood volume. Department of Biology, Bryn Mawr College (1926)Google Scholar
- 8.Wolański, W., Gzik-Zroska, B., Joszko, K., Kawlewska, E., Sobkowiak, M., Gzik, M., Kaspera, W.: Impact of vessel mechanical properties on hemodynamic parameters of blood flow. In: Gzik, M., Tkacz, E., Paszenda, Z., Piętka, E. (eds.) Proceedings of the Innovations in Biomedical Engineering, IiBE 2017, pp. 271–278. Springer, Cham (2018)Google Scholar
- 9.Wolański, W., Gzik-Zroska, B., Joszko, K., Gzik, M., Sołtan, D.: Numerical analysis of blood flow through artery with elastic wall of vessel. In: Gzik, M., Tkacz, E., Paszenda, Z., Piętka, E. (eds.) Proceedings of the Innovations in Biomedical Engineering, IiBE 2017, pp. 193–200. Springer, Cham (2017)Google Scholar