Endoscopic Submucosal Dissection



Endoscopic submucosal dissection is a novel technique that aims en bloc removal of superficial gastrointestinal lesions. It consists of basic steps of injection and lifting the mucosa from the submucosa, incision and dissection of the lesion, and snare removal. It allows for a complete sample to be removed with negative margins that is suitable for accurate histopathological diagnosis. This newer advanced endoscopic technique will be explained in detail along with key points in this chapter.


Endoscopic submucosal dissection Colonoscopy Lesion removal Cost of endoscopic submucoal dissection Injection material 



Endoscopic mucosal resection


Endoscopic submucosal dissection


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Supplementary material

Video 2.1

Video demonstrating steps of endoscopic submucosal dissection on a complex ileocecal valve lesion (MP4 66499 kb)

Video 2.2

Video demonstrating balloon-assisted resection technique being used during endoscopic submucosal dissection to stabilize the surgical field and achieve retraction (MP4 175051 kb)

Video 2.3

Video demonstrating closure of the defect with clip application after endoscopic submucosal dissection (MP4 128395 kb)

Video 2.4

Video demonstrating over-the-scope clip application to close a defect after endoscopic submucosal dissection (MP4 129996 kb)


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of Colorectal SurgeryCleveland ClinicClevelandUSA

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