Surgery or Radiation Therapy for Early Stage Glottic Cancer

  • Semirra BayanEmail author
Part of the Difficult Decisions in Surgery: An Evidence-Based Approach book series (DDSURGERY)


Laryngeal carcinoma is one of the most common upper aerodigestive tract malignancies. Given its early stage, high cure rate, and low concern for metastasis, early glottic carcinoma is unique in that the focus is not only on an oncologically sound method of treatment but one that also optimizes voice outcomes. There is often debate over the benefit of transoral laser microsurgery versus radiation in the treatment of these cancers. Therefore, a systematic analysis of the literature was performed comparing radiation treatment versus transoral laser microsurgery (TLM). Given superior laryngeal preservation rates and otherwise equivalent oncologic outcomes, TLM should be considered for T1 glottic cancers in medically appropriate patients able to tolerate general anesthesia.


Early glottic cancer Radiation Oncologic outcomes Voice outcomes 


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© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of Otolaryngology Head and Neck SurgeryMayo ClinicRochesterUSA

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