Bone Tumors

  • K. Mohan Iyer


This chapter gives details regarding the staging of the tumor, cartilage lesions cysts, bone forming tumors, plasma cell dyscrasias, multiple myeloma, metastasis, management in the various forms of chemotherapy or surgery.


Staging Cartilage forming tumors Bone forming tumors Cysts Metastasis Chemotherapy 


  1. 1.
    Enneking WF, et al. A system for the surgical staging of musculoskeletal sarcoma. Clin Orthop Relat Res. 1980;153:106–20.Google Scholar
  2. 2.
    Campanacci M. Bone and soft tissue tumors: clinical features, imaging, pathology and treatment. 2nd ed. New York: Springer; 1999.CrossRefGoogle Scholar
  3. 3.
    Giant cell tumor. In: Orthopaedics one—The Orthopaedic Knowledge Network. Created 21 May 2008;16:14.Google Scholar
  4. 4.
    Jaffe HL. Osteoid osteoma: a benign osteoblastic tumor composed of osteoid and atypical bone. Arch Surg. 1935;31:709–28.CrossRefGoogle Scholar
  5. 5.
    Wells RG, Miller JH, Sty JR. Scintigraphic patterns in osteoid osteoma and spondylolysis. Clin Nucl Med. 1987;12:39–44.CrossRefPubMedGoogle Scholar
  6. 6.
    Atar D, Lehman WB, Grant AD. Tips of the trade. Computerized tomography: guided excision of osteoid osteoma. Orthop Rev. 1992;21(12):1457–8.PubMedGoogle Scholar
  7. 7.
    Jaffe HL, Lichtenstein L, Portis RB. Giant cell tumor of bone: its pathological appearance, grading, supposed variants and treatment. Arch Pathol. 1940;30:993–1031.Google Scholar
  8. 8.
    Sanerkin NG. Malignancy, aggressiveness, and recurrence in giant cell tumor of bone. Cancer. 1980;46:1641–9.CrossRefPubMedGoogle Scholar
  9. 9.
    Salzer-Kuntschik M, Delling G, Beron G, Sigmund R. Morphological grades of regression in osteosarcoma after polychemotherapy study COSS 80. J Cancer Res Clin Oncol. 1983;106(Suppl):21–4.CrossRefPubMedGoogle Scholar
  10. 10.
    Picci P, Rougraff BT, Bacci G, et al. Prognostic significance of histopathologic response to chemotherapy in nonmetastatic Ewing’s sarcoma of the extremities. J Clin Oncol. 1993;11:1763–9.CrossRefPubMedGoogle Scholar
  11. 11.
    Huvos AG. Bone tumors: diagnosis, treatment, and prognosis. 2nd ed. Philadelphia, PA: W.B. Saunders; 1990.Google Scholar
  12. 12.
    Davidson AW, Hong A, McCarthy SW, Stalley PD. En-bloc resection, extracorporeal irradiation, and re-implantation in limb salvage for bony malignancies. J Bone Joint Surg Br. 2005;87:851–7.CrossRefPubMedGoogle Scholar
  13. 13.
    Poffyn B, Sys G, Mulliez A, Van Maele G, Van Hoorebeke L, Forsyth R, et al. Extracorporeally irradiated autografts for the treatment of bone tumours: tips and tricks. Int Orthop. 2011;35:889–95.CrossRefPubMedGoogle Scholar
  14. 14.
    Durie BG, Salmon SE. A clinical staging system for multiple myeloma: correlation of measured myeloma cell mass with presenting clinical features, response to treatment, and survival. Cancer. 1975;36:842–54.CrossRefGoogle Scholar
  15. 15.
    Soutar R, Lucraft H, Jackson G, Reece A, Bird J, Low E, Samson D. Guidelines on the diagnosis and management of solitary plasmacytoma of the bone and solitary extramedullairy plasmacytoma. Br J Haematol. 2004;124:717–26.CrossRefPubMedGoogle Scholar

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© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • K. Mohan Iyer
    • 1
  1. 1.Royal Free Hampstead NHS Trust, Royal Free HospitalLondonUK

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