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Definition of Refractory Chronic Headache

  • Andrea NegroEmail author
  • Dimos Dimitrios Mitsikostas
Chapter
Part of the Headache book series (HEAD)

Abstract

Physicians, researchers and clinical trial developers from around the world, working in the headache field, speak a common language based on the International Classification of Headache Disorders (ICHD). The current ICHD-3 does not include a definition of refractoriness for primary headaches. To fill the gap, the European Headache Federation (EHF) developed new consensus criteria for refractory chronic migraine (rCM) and refractory chronic cluster headache (rCCH) particularly for the purposes of randomized-controlled trials (RCTs) involving experimental medications and neuromodulation, but they may also help for referral from a primary care provider to a headache specialist and for medical cost reimbursement. EHF definitions of rCM and rCCH have to be considered as a useful and mandatory tool in any multidisciplinary or innovative therapeutic approach.

Keywords

Refractory chronic headache Refractory chronic migraine Refractory chronic cluster headache 

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Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.Department of Clinical and Molecular MedicineRegional Referral Headache Centre, Sant’Andrea Hospital, Sapienza University of RomeRomeItaly
  2. 2.Department of NeurologyAeginition Hospital, National and Kapodistrian University of AthensAthensGreece

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