Interesting Case Reports in ROP from the Literature



This chapter summarizes case reports about ROP treatment failures from the literature.


Pediatric retinal diseases ROP Case reports 


  1. 1.
    Snyder LL, Garcia-Gonzalez JM, Shapiro MJ, Blair MP. Very late reactivation of retinopathy of prematurity after monotherapy with Intravitreal Bevacizumab. Ophthalmic Surg Lasers Imaging Retina. 2016;47:280–3.CrossRefGoogle Scholar
  2. 2.
    Hajrasouliha AR, Garcia-Gonzales JM, Shapiro MJ, Yoon H, Blair MP. Reactivation of retinopathy of prematurity three years after treatment with Bevacizumab. Ophthalmic Surg Lasers Imaging Retina. 2017;48:255–9.CrossRefGoogle Scholar
  3. 3.
    Paulus YM, Moshfeghi DM. Persistent plus disease after laser in retinopathy of prematurity with tetralogy of Fallot. Eur J Ophthalmol. 2013;23:764–6.CrossRefGoogle Scholar
  4. 4.
    Gunay M, Yavuz T, Celik G, Uludag G. Persistence of retinopathy of prematurity in an infant with tetralogy of fallot. Case Rep Pediatr. 2016;2016:7070316.PubMedPubMedCentralGoogle Scholar
  5. 5.
    Wang J, Xiang D. Early clinical characteristics of bacterial endophthalmitis in retinopathy of prematurity after intravitreal bevacizumab injection: a case report. Exp Ther Med. 2017;13:3563–6.CrossRefGoogle Scholar
  6. 6.
    Ehmann D, Greve M. Intravitreal bevacizumab for exudative retinal detachment post laser therapy for retinopathy of prematurity. Can J Ophthalmol. 2014;49:228–31.CrossRefGoogle Scholar
  7. 7.
    Cabrera MT, Brewer EM, Grant L, Tarczy-Hornoch K. Exudative retinal detachment documented by handheld spectral domain optical coherence tomography after retinal laser photocoagulation for retinopathy of prematurity. Retin Cases Brief Rep. 2018;
  8. 8.
    Chhablani J, Rani PK, Balakrishnan D, Jalali S. Unusual adverse choroidal reaction to intravitreal bevacizumab in aggressive posterior retinopathy of prematurity: the Indian Twin Cities ROP screening (ITCROPS) data base report number 7. Semin Ophthalmol. 2014;29:222–5.CrossRefGoogle Scholar
  9. 9.
    Menke MN, Framme C, Nelle M, Berger MR, Sturm V, Wolf S. Intravitreal ranibizumab monotherapy to treat retinopathy of prematurity zone II, stage 3 with plus disease. BMC Ophthalmol. 2015;15:20.CrossRefGoogle Scholar
  10. 10.
    Wu WC, Yeh PT, Chen SN, Yang CM, Lai CC, Kuo HK. Effects and complications of bevacizumab use in patients with retinopathy of prematurity: a multicenter study in taiwan. Ophthalmology. 2011;118:176–83.CrossRefGoogle Scholar
  11. 11.
    Atchaneeyasakul LO, Trinavarat A. Choroidal ruptures after adjuvant intravitreal injection of bevacizumab for aggressive posterior retinopathy of prematurity. J Perinatol. 2010;30:497–9.CrossRefGoogle Scholar

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© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.OphthalmologyUniversity of Uppsala OphthalmologyUppsalaSweden
  2. 2.Department of OphthalmologySamsung Medical Center, Sungkyunkwan UniversitySeoulSouth Korea

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