Interesting Case Reports in ROP from the Literature

  • Ulrich Spandau
  • Sang Jin Kim


This chapter summarizes case reports about ROP treatment failures from the literature.


Pediatric retinal diseases ROP Case reports 


  1. 1.
    Snyder LL, Garcia-Gonzalez JM, Shapiro MJ, Blair MP. Very late reactivation of retinopathy of prematurity after monotherapy with Intravitreal Bevacizumab. Ophthalmic Surg Lasers Imaging Retina. 2016;47:280–3.CrossRefGoogle Scholar
  2. 2.
    Hajrasouliha AR, Garcia-Gonzales JM, Shapiro MJ, Yoon H, Blair MP. Reactivation of retinopathy of prematurity three years after treatment with Bevacizumab. Ophthalmic Surg Lasers Imaging Retina. 2017;48:255–9.CrossRefGoogle Scholar
  3. 3.
    Paulus YM, Moshfeghi DM. Persistent plus disease after laser in retinopathy of prematurity with tetralogy of Fallot. Eur J Ophthalmol. 2013;23:764–6.CrossRefGoogle Scholar
  4. 4.
    Gunay M, Yavuz T, Celik G, Uludag G. Persistence of retinopathy of prematurity in an infant with tetralogy of fallot. Case Rep Pediatr. 2016;2016:7070316.PubMedPubMedCentralGoogle Scholar
  5. 5.
    Wang J, Xiang D. Early clinical characteristics of bacterial endophthalmitis in retinopathy of prematurity after intravitreal bevacizumab injection: a case report. Exp Ther Med. 2017;13:3563–6.CrossRefGoogle Scholar
  6. 6.
    Ehmann D, Greve M. Intravitreal bevacizumab for exudative retinal detachment post laser therapy for retinopathy of prematurity. Can J Ophthalmol. 2014;49:228–31.CrossRefGoogle Scholar
  7. 7.
    Cabrera MT, Brewer EM, Grant L, Tarczy-Hornoch K. Exudative retinal detachment documented by handheld spectral domain optical coherence tomography after retinal laser photocoagulation for retinopathy of prematurity. Retin Cases Brief Rep. 2018;
  8. 8.
    Chhablani J, Rani PK, Balakrishnan D, Jalali S. Unusual adverse choroidal reaction to intravitreal bevacizumab in aggressive posterior retinopathy of prematurity: the Indian Twin Cities ROP screening (ITCROPS) data base report number 7. Semin Ophthalmol. 2014;29:222–5.CrossRefGoogle Scholar
  9. 9.
    Menke MN, Framme C, Nelle M, Berger MR, Sturm V, Wolf S. Intravitreal ranibizumab monotherapy to treat retinopathy of prematurity zone II, stage 3 with plus disease. BMC Ophthalmol. 2015;15:20.CrossRefGoogle Scholar
  10. 10.
    Wu WC, Yeh PT, Chen SN, Yang CM, Lai CC, Kuo HK. Effects and complications of bevacizumab use in patients with retinopathy of prematurity: a multicenter study in taiwan. Ophthalmology. 2011;118:176–83.CrossRefGoogle Scholar
  11. 11.
    Atchaneeyasakul LO, Trinavarat A. Choroidal ruptures after adjuvant intravitreal injection of bevacizumab for aggressive posterior retinopathy of prematurity. J Perinatol. 2010;30:497–9.CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Ulrich Spandau
    • 1
  • Sang Jin Kim
    • 2
  1. 1.OphthalmologyUniversity of Uppsala OphthalmologyUppsalaSweden
  2. 2.Department of OphthalmologySamsung Medical Center, Sungkyunkwan UniversitySeoulSouth Korea

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