Neoadjuvant therapy consists of the preoperative administration of systemic treatment in patients with nonmetastatic breast cancer (BC). The term neoadjuvant chemotherapy (neoChT) does not adequately reflect the wide range of possibilities for systemic treatment that can be employed in this setting—such as endocrine therapy and new target therapies—being “technically more appropriate” to use neoadjuvant systemic therapy (NST); see Table 1.
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