• Radiá Pereira dos Santos
  • Bruno Hochhegger


Mammography is the best method available for early diagnosis of breast cancer, showing a reduction in mortality due to screening studies.

Recommended Literature

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    Autier P, Héry C, Haukka J, Boniol M, Byrnes G. Advanced breast cancer and breast cancer mortality in randomized controlled trials on mammography screening. J Clin Oncol. 2009;27(35):5919–23. Meta-analysis of large randomized studies demonstrating that for each unit of reduction in the incidence of advanced breast cancer, there was a reduction in mortality from breast cancer CrossRefGoogle Scholar
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    Giess CS, Frost EP, Birdwell RL. Difficulties and errors in diagnosis of breast neoplasms. Semin Ultrasound CT MR. 2012;33(4):288–99. Excellent review demonstrating the major limitations and difficulties of radiological diagnosis in mammography CrossRefGoogle Scholar
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    Gøtzsche PC, Nielsen M. Screening for breast cancer with mammography. Cochrane Database Syst Rev. 2009;4:CD001877. Meta-analysis of eight studies including 600,000 women included. The final demonstration showed decrease in mortality from breast cancer estimated by 15% relative risk. The reduction in overall mortality was 0.5% Google Scholar
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    Granader EJ, Dwamena B, Carlos RC. MRI and mammography surveillance of women at increased risk for breast cancer: recommendations using an evidence-based approach. Acad Radiol. 2008;15(12):1590–5. Meta-analysis that evaluated imaging methods in women with risk factors for breast cancer. In women with an increased risk without the BRCA gene, magnetic resonance (MR) cancer detection rates were 0.011 (95% confidence interval [CI] 0.003–0.019), through mammogram 0.005 (95% CI 0.002–0.008), and by a combination of through, 0.012 (95% CI 0.004–0.020). The data support an essential role of MRI in women with an increased risk for breast cancer. CrossRefGoogle Scholar
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    Pisano ED, Gatsonis C, Hendrick E, Yaffe M, Baum JK, Acharyya S, et al. Diagnostic performance of digital versus mammography film for breast-cancer screening. N Engl J Med. 2005;353(17):1773–83. A study comparing digital and analog mammography that included 49,528 asymptomatic women at 33 sites in the United States and Canada. The overall diagnostic accuracy of digital mammography was similar, but digital mammography was more accurate in women younger than 50 years, in women with radiologically dense breasts and premenopausal or perimenopausal women CrossRefGoogle Scholar
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    Smith RA, Duffy SW, Tabor L. Breast cancer screening: the evolving evidence. Oncology (Williston Park). 2012;26(5):471–5, 479–81, 485–6. Excellent review that discusses the latest studies in the area, discussing the orientations of the larger societies Google Scholar

Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Radiá Pereira dos Santos
    • 1
  • Bruno Hochhegger
    • 2
  1. 1.RadiologyBrazilian Radiology CollegePorto AlegreBrazil
  2. 2.RadiologyCatholic UniversityPorto AlegreBrazil

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