Obstructive Sleep Apnea Syndrome

  • Manisha Budhdeo Witmans


Humans spend about one third of a lifetime sleeping. We have learned a great deal about sleep and sleep disorders since the discovery of REM sleep in 1953. It is well known that obstructive sleep apnea (OSA) is a sleep-related disorder in which affected individuals struggle to breath at night, and have associated cardiopulmonary, metabolic, and psychological consequences resulting in increased morbidity and mortality. As many as 1.2–7.5% of different populations have been reported to have obstructive sleep apnea (apnea hypopnea index of >5/hr) and associated hypersomnolence. The variability in the prevalence is related to the lack of homogeneity in different studies. This chapter will highlight the developments in treating obstructive sleep apnea while discussing some of the challenges that this chronic disease poses in the era of personalized medicine.


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© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Manisha Budhdeo Witmans
    • 1
  1. 1.University of AlbertaEdmontonCanada

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