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Target Gene Mining Algorithm Based on gSpan

  • Liangfu Lu
  • Xiaoxu Ren
  • Lianyong QiEmail author
  • Chenming Cui
  • Yichen Jiao
Conference paper
Part of the Lecture Notes of the Institute for Computer Sciences, Social Informatics and Telecommunications Engineering book series (LNICST, volume 268)

Abstract

In recent years, the focus of bioinformatics research has turned to biological data processing and information extraction. New mining algorithm was designed to mine target gene fragment efficiently from a huge amount of gene data and to study specific gene expression in this paper. The extracted gene data was filtered in order to remove redundant gene data. Then the binary tree was constructed according to the Pearson correlation coefficient between gene data and processed by gSpan frequent subgraph mining algorithm. Finally, the results were visually analyzed in grayscale image way which helped us to find out the target gene. Compared with the existing target gene mining algorithms, such as integrated decision feature gene selection algorithm, our approach enjoys the advantages of higher accuracy and processing high-dimensional data. The proposed algorithm has sufficient theoretical basis, not only makes the results more efficient, but also makes the possibility of error results less. Moreover, the dimension of the data is much higher than the dimension of the data set used by the existing algorithm, so the algorithm is more practical.

Keywords

gSpan gene mining algorithm Gene expression data Data mining Visual analysis 

Notes

Acknowledgments

This work was partially supported by the National Natural Science Foundation of China under No. 51877144 and No. 61872219.

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Copyright information

© ICST Institute for Computer Sciences, Social Informatics and Telecommunications Engineering 2019

Authors and Affiliations

  • Liangfu Lu
    • 1
  • Xiaoxu Ren
    • 1
  • Lianyong Qi
    • 2
    Email author
  • Chenming Cui
    • 3
  • Yichen Jiao
    • 3
  1. 1.School of MathematicsTianjin UniversityTianjinChina
  2. 2.School of Information Science and EngineeringQufu Normal UniversityRizhaoChina
  3. 3.School of SoftwareTianjin UniversityTianjinChina

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