About 15–30% of colorectal cancer present as obstruction or perforation in an emergency setting.
Several studies reported a more advanced stage as well as a more aggressive profile compared to the elective cases.
This review focuses on tumor pathology as a basis for different survival outcomes.
In particular the staging categories T, N, and M as well as the non-anatomic, morphological prognostic factors (tumor grade, lymphovascular invasion) and the TNM ancillary R (residual disease) are discussed.
Careful pathological examination is necessary to confirm the clinical presentation (advanced T category, obstruction, perforation) and to correctly assess nodal staging.
Colorectal cancer emergency pathology
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