Emergencies Related to Advanced Metastatic Colorectal Cancer

  • Riccardo Memeo
  • Alessandro Verbo
  • Patrick Pessaux
  • Emanuele Felli
Part of the Hot Topics in Acute Care Surgery and Trauma book series (HTACST)


Metastatic liver cancer is often associated with complications associed with the progression of the pathology. The menagement of such complication is problematic, considering the fragility ot the patient. This chapter want to clearify the management of this life-threatening complications.


Complications Metastatic liver cancer Management 


  1. 1.
    Abercrombie J. Hemorrhage of the liver. Lond Med Gaz. 1844;34:792–4.Google Scholar
  2. 2.
    Battula N, Tsapralis D, Takhar A, et al. Aetio-pathogenesis and the management of spontaneous liver bleeding in the West: a 16-year single-centre experience. HPB. 2012;14:382–9.CrossRefGoogle Scholar
  3. 3.
    Schoedel KE, Dekker A. Hemoperitoneum in the setting of metastatic cancer to the liver. A report of two cases with review of the literature. Dig Dis Sci. 1992;37:153–4.CrossRefGoogle Scholar
  4. 4.
    Tung CF, Chang CS, Chow WK, Peng YC, Hwang JI, Wen MC. Hemoperitoneum secondary to spontaneous rupture of metastatic epidermoid carcinoma of liver: case report and review of the literature. Hepatogastroenterology. 2002;49:1415–7.PubMedGoogle Scholar
  5. 5.
    Sohda T, Hanano T, Miyamoto H, Kitano Y, Iwata K, Yokoyama M, Irie M, Takeyama Y, Shakado S, Sakisaka S. Spontaneous rupture of metastatic alpha-fetoprotein-producing gastric cancer of the liver. Hepatol Int. 2008;2:258–61.CrossRefGoogle Scholar
  6. 6.
    Duan Y, et al. Spontaneous rupture of hepatic metastasis from small cell neuroendocrine carcinoma of maxillary sinus. World J Surg Oncol. 2014;12:126.CrossRefGoogle Scholar
  7. 7.
    Quinn L, Bagia S. Effective palliation of obstructive jaundice due to colorectal cancer liver metastasis. ANZ J Surg. 2014;84(6):493–4. Available from: Scholar
  8. 8.
    Traeger L, Kiroff G. Intrabiliary obstruction by colorectal metastases. J Surg Case Rep. 2018;2018(1):rjx259. Available from:
  9. 9.
    Kim KM, Park JW, Lee JK, Lee KH, Lee KT, Shim SG. A comparison of preoperative biliary drainage methods for perihilar cholangiocarcinoma: endoscopic versus percutaneous transhepatic biliary drainage. Gut Liver. 2015;9(6):791. Available from: Scholar
  10. 10.
    Sawas T, Al Halabi S, Parsi MA, Vargo JJ. Self-expandable metal stents versus plastic stents for malignant biliary obstruction: a meta-analysis. Gastrointest Endosc. 2015;82(2):256–267.e7. Available from: Scholar
  11. 11.
    Niu H, Gao W, Cheng J, Liu B, Li Y, Huang K, et al. Improvement of percutaneous transhepatic biliary internal-external drainage and its initial experience in patients with malignant obstruction of the upper biliary tree. Hepatogastroenterology. 2011;59(117):1368–73. Available from:
  12. 12.
    Green MH, Duell RM, et al. Comprehensive summary of case series reports on presentation, etiology, evaluation, and management of hemobilia. Br J Surg. 2001;88:773–86.CrossRefGoogle Scholar
  13. 13.
    Zaydfudim VM, Angle JF, et al. Current management of hemobilia. Curr Surg Rep. 2014;2:54.CrossRefGoogle Scholar
  14. 14.
    Chin MW, Enns R. Hemobilia. Curr Gastroenterol Rep. 2010;12:121–9.CrossRefGoogle Scholar
  15. 15.
    Defreyne L, Vanlangenhove P, De Vos M, et al. Embolization as a first approach with endoscopically unmanageable acute nonvariceal gastrointestinal hemorrhage. Radiology. 2001;218:739–48.CrossRefGoogle Scholar
  16. 16.
    Lardière-Deguelte S, Ragot E, Amroun K, Piardi T, Dokmak S, Bruno O, et al. Hepatic abscess: diagnosis and management. J Visc Surg. 2015;152(4):231–43. Available from: Scholar
  17. 17.
    Law S-T, Li KK. Is hepatic neoplasm-related pyogenic liver abscess a distinct clinical entity? World J Gastroenterol. 2012;18(10):1110–6. Available from: Scholar
  18. 18.
    Yamamoto J, Sugihara K, et al. Pathologic support for limited hepatectomy in the treatment of liver metastasis from colorectal cancer. Ann Surg. 1995;221:74–8.CrossRefGoogle Scholar
  19. 19.
    Tada K, Kokudo N, Seki M, et al. Hepatic resection for colorectal metastasis with macroscopic tumor thrombus in the portal vein. World J Surg. 2003;27:299–303.CrossRefGoogle Scholar
  20. 20.
    Shintani D, Tajima Y, Baba H, et al. Colon cancer with portal vein tumor thrombosis-a case report and review of the literature. Gan To Kagaku Ryoho. 2012;39(2):2243–5.PubMedGoogle Scholar
  21. 21.
    Furuyama H, Fuji H, Okumura S, et al. A case of recurrent colon cancer developed thrombus in superior mesenteric vein after chemotherapy. Gan To Kagaku Ryoho. 2013;40:659–61.PubMedGoogle Scholar
  22. 22.
    Yamamoto N, et al. Massive portal vein tumor thrombus from colorectal cancer without any metastatic nodules in the liver parenchyma. Rare Tumors. 2011;3(4):e47.CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Riccardo Memeo
    • 1
  • Alessandro Verbo
    • 2
  • Patrick Pessaux
    • 3
  • Emanuele Felli
    • 3
  1. 1.Department of Emergency and Organ Transplantation, Institute of General Surgery and Liver TransplantationUniversity of BariBariItaly
  2. 2.Hepato-Biliary and Pancreatic Surgical Unit, Miulli HospitalBariItaly
  3. 3.Hepato-Biliary and Pancreatic Surgical Unit, General, Digestive, and Endocrine Surgery, IRCAD, Strasbourg’s IHU (Institute for Minimally Invasive Image-Guided Surgery)University of StrasbourgStrasbourgFrance

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