Sorbitol Demineralization by Ion Exchange
Sorbitol is a sugar alcohol commonly known as D-glucitol. It is synthesized from glucose by a reduction reaction altering the aldehyde group to a hydroxyl group. The body slowly metabolizes sorbitol, minimizing the possibility of increasing the insulin level, and this makes it a good sweetener for diabetic patients. Sorbitol finds diverse applications in the food industry, and its purity is a significant factor to be considered before it is used as an additive to food. Various types of ion-exchange and membrane technologies have been applied for purifying this compound. This chapter is aimed to illustrate the different ion-exchange chromatographic techniques for demineralization/deashing of sorbitol with future perspectives.
KeywordsIon exchange Sorbitol Food industry Demineralization Membrane filtration
SBU and Rijeeba would like to acknowledge the Institute of Bioresources and Sustainable Development, a national institute under DBT, Government of India, for providing help and support. Raveendran Sindhu acknowledges the Department of Science and Technology for sanctioning a project under DST WOS-B scheme. Raveendran Sindhu and Parameswaran Binod acknowledge EPFL, Lausanne, Switzerland, for providing visiting fellowship.
- 1.Marques C,Tarek R, Sara M, Brar SK (2016) Sorbitol production from biomass and its global market platform chemical biorefinery, First Edition, p 217–227Google Scholar
- 3.Celligoi, MAPC, Borsari RRJ, Buzato JB, Silva RSDSFD (2010) Evaluation of supplementation of sucrose medium on the synthesis of Zymomonas mobilisbio-products. Acta Scientiarum Biol Sci 32Google Scholar
- 8.Rowe RC, Sheskey PJ, Quinn ME (2009) Handbook of pharmaceutical Excipients. Pharmaceutical Press. Sambhakar S, Singh B, Paliwal S, Mishra PR (2012) Sorbitol based proniosomes to improve permeability and stability of an oral CephalosporinGoogle Scholar
- 9.Schiweck HEA (2008) Ullmann’s encyclopedia of industrial chemistry. John Wiley & Sons, Sugar AlcoholsGoogle Scholar
- 10.Dies RC, Kearsley MW (2012) Sorbitol and Mannitol. Sweeteners and sugar alternatives in food technology. Ames Oxford 2:249–261Google Scholar
- 15.Radhika GS, Moorthy SN (2009) Sugar alcohols—a review. Trends Carbohydr Res 1:71–79Google Scholar
- 18.Saniocki I, Sakmann A, Leopold CS (2013) Evaluation of the suitability of various lubricants for direct compaction of sorbitol tablet formulations. J Excipients Food Chem 4:169–182Google Scholar
- 19.Sambhakar S, Singh B, Paliwal S, Mishra PR (2012) Sorbitol based proniosomes to improve the permeability andstability of an oral Cephlosp orinGoogle Scholar
- 21.Aminah A, Jusoff K, St.Hadijah, Nuraeni R., Palad Marliana S, Muchtar AH, Nonci, M(2013) Increasing soybean (glycine max L) drought resistant with osmolit sorbitol. Mod Appl Sci 7:78–85Google Scholar
- 23.Bhusnure OG, Mali SN (2015) Recent trends in ion exchange chromatography. Int J Pharm Drug Anal 3(12):403–416Google Scholar