Fluid Management in Acute Kidney Injury

  • M. OstermannEmail author
  • A. More
  • S. Jog
Part of the Annual Update in Intensive Care and Emergency Medicine book series (AUICEM)


Acute kidney injury (AKI) is very common during critical illness affecting >50% of patients and associated with increased morbidity and mortality and high health care costs [1]. The traditional strategy for managing patients at risk or with established AKI often involves high volume fluid administration due to fear of untreated hypovolemia [2]. Whilst timely fluid administration may be beneficial if AKI is indeed precipitated by intravascular volume depletion, there is increasing evidence that excessive fluid resuscitation beyond correction of hypovolemia leads to adverse outcomes, including worsening of renal function [3–6]. Furthermore, there is clear evidence that certain types of fluids are nephrotoxic [3, 6–9].


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of Critical CareKing’s College London, Guy’s & St Thomas’ HospitalLondonUK
  2. 2.Division of Critical CareChristian Medical College HospitalVelloreIndia
  3. 3.Department of Critical CareDeenanath Mangeshkar Hospital and Research CenterPuneIndia

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