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Mechanical Circulatory Support Devices for Cardiogenic Shock: State of the Art

  • L. A. HajjarEmail author
  • J.-L. Teboul
Chapter
Part of the Annual Update in Intensive Care and Emergency Medicine book series (AUICEM)

Abstract

Cardiogenic shock is the clinical expression of circulatory failure, as a consequence of left, right or biventricular dysfunction. Cardiogenic shock is also defined as a state of critical end-organ hypoperfusion due to primary cardiac dysfunction [1–3]. Cardiogenic shock is not simply a decrease in cardiac contractile function, but also a multiorgan dysfunction syndrome involving the entire circulatory system, often complicated by a systemic inflammatory response syndrome with severe cellular and metabolic abnormalities [4]. The clinical presentation of cardiogenic shock varies from hemodynamic abnormalities of pre-shock to mild shock, progressing to more profound shock and finally refractory shock, which invariably is associated with high mortality rates. Additional insults can occur, such as arrhythmias, vasodilation, ischemia and infection, acutely changing the trajectory of the disease [5]. The contemporary management of cardiogenic shock involves early diagnosis and directed therapy to optimize oxygen delivery and tissue perfusion.

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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of CardiopneumologyInstituto do Coracao, Universidade de São PauloSao PauloBrazil
  2. 2.Cardiologic Intensive Care UnitHospital SirioLibanesSao PauloBrazil
  3. 3.Faculté de Médecine Paris-SudUniversite Paris-SudLe Kremlim-BicêtreFrance
  4. 4.Service de reánimation médicale, Hôpitaux Universitaires Paris-Sud, Hôpital de BicêtreLe Kremlin-BicêtreFrance
  5. 5.Inserm UMR_S999Le Plessis-RobinsonFrance

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