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CardioModel – New Software for Cardiac Electrophysiology Simulation

  • Valentin Petrov
  • Sergey Lebedev
  • Anna Pirova
  • Evgeniy Vasilyev
  • Alexander Nikolskiy
  • Vadim Turlapov
  • Iosif Meyerov
  • Grigory OsipovEmail author
Conference paper
Part of the Communications in Computer and Information Science book series (CCIS, volume 965)

Abstract

The rise of supercomputing technologies during the last decade has enabled significant progress towards the invention of a personal biologically relevant computer model of a human heart. In this paper we present a new code for numerical simulation of cardiac electrophysiology on supercomputers. Having constructed a personal segmented tetrahedral grid of the human heart based on a tomogram, we solve the bidomain equations of cardiac electrophysiology using the finite element method thus achieving the goal of modeling of the action potential propagation in heart. Flexible object-oriented architecture of the software allows us to expand its capabilities by using relevant cell models, preconditioners and numerical methods for solving SLAEs. The results of numerical modeling of heart under normal conditions as well as a number of simulated pathologies are in a good agreement with theoretical expectations. The software achieves at least 75% scaling efficiency on the 120 ranks on the Lobachevsky supercomputer.

Keywords

Heart simulation Cardiac electrophysiology Bidomain model Finite element method Numerical analysis Parallel computing 

Notes

Acknowledgements

The study was supported by the Ministry of Education of Russian Federation (Contract # 02.G25.31.0157, date 01.12.2015).

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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Valentin Petrov
    • 1
  • Sergey Lebedev
    • 1
  • Anna Pirova
    • 1
  • Evgeniy Vasilyev
    • 1
  • Alexander Nikolskiy
    • 1
    • 2
  • Vadim Turlapov
    • 1
  • Iosif Meyerov
    • 1
  • Grigory Osipov
    • 1
    Email author
  1. 1.Lobachevsky State University of Nizhni NovgorodNizhny NovgorodRussia
  2. 2.Nizhni Novgorod State Medical AcademyNizhny NovgorodRussia

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