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Microwave-Assisted Solid-State Synthesis of Fluorinated Hydroxyapatite

  • Qian Peng
  • Huimin Tang
  • Zhangui TangEmail author
  • Zhiwei PengEmail author
Conference paper
Part of the The Minerals, Metals & Materials Series book series (MMMS)

Abstract

As an important inorganic component of vertebrate bones and teeth, hydroxyapatite (HA) has excellent biocompatibility, bioactivity, osteoconductivity and chemical stability, and can be used as a drug-release carrier and bone tissue engineering repair material. However, when it is used alone, it often presents a few disadvantages such as large brittleness, low fatigue resistance, and easy agglomeration. In this study, to improve its mechanical properties fluorinated hydroxyapatite (FHA) was synthesized by doping fluorine ion in nanocrystalline HA in solid state through microwave sintering of the mixture of HA and MgF2 in the presence of water as an adhesive agent. The X-ray diffraction (XRD), scanning electron microscopy (SEM), and Fourier-transform infrared spectroscopy (FTIR) analyses were performed to explore the formation mechanism of FHA from HA under microwave irradiation.

Keywords

Hydroxyapatite Fluorination Microwave sintering Synthesis Mechanical properties 

Notes

Acknowledgements

This work was partially supported by the Fundamental Research Funds for the Central Universities of Central South University under Grant 2018zzts040, the Co-Innovation Center for Clean and Efficient Utilization of Strategic Metal Mineral Resources under Grant 2014-405, the Innovation-Driven Program of Central South University under Grant 2016CXS021, and the Shenghua Lieying Program of Central South University under Grant 502035001.

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Copyright information

© The Minerals, Metals & Materials Society 2019

Authors and Affiliations

  1. 1.Xiangya Stomatological Hospital, Central South UniversityChangshaChina
  2. 2.School of Xiangya StomatologyCentral South UniversityChangshaChina
  3. 3.School of Minerals Processing and BioengineeringCentral South UniversityChangshaChina

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