Advertisement

Phytomediated Synthesis of Cerium Oxide Nanoparticles and Their Applications

  • Annu
  • Akbar Ali
  • Rahul Gadkari
  • Javed N. Sheikh
  • Shakeel Ahmed
Chapter

Abstract

Nanotechnology has evolved with synthetic as well as natural precursors, and nanomaterials can be obtained either naturally/incidentally or through engineering. Cerium oxide nanoparticles (CeO NPs) have found vast applications in various fields of science and technology, extending from electronics to structural engineering, agriculture and medicine. Conventionally, CeO NPs were synthesized by physical and chemical methods such as hydrothermal, flame spray pyrolysis, sonochemical, microwave, solgel, co-precipitation, etc., using chemicals as the reducing and stabilizing agents, which carry with them various biological and environmental risks due to their toxicity. Biological synthesis of NPs, using plants and microbes as a source of precursor material, is emerging as a safe and green alternative. The use of plant extracts is relatively more convenient and safer for this purpose in comparison to microbes. It also reduces the cost of maintaining the microorganisms’ isolation and culture. The ideal protocol provides a better control of shapes, sizes and dispersivity of metal nanoparticles and reduces the need for purification of the manufactured NPs, thus ridding from the extensive use of organic solvents. Synthesis of CeO NPs by utilizing the plant extract aqueous solution has gained ground due to having no adverse effect on the environment. These nanoparticles have shown their immense applications in the fields of photocatalysis and biomedicine. Due to their small size and free radical scavenging properties, they also find use in areas concerning the catalysts, sensors, solid oxide fuel cells, sun screen cosmetics, biotransformation and bioimaging and in the antioxidant and antibacterial treatments. Moreover, they provide excellent material for coating and polishing.

Keywords

Nanoceria Phytosynthesis Plant extract NP applications 

Abbreviations

AZO

Azodicarbonamide

CeO NPs

Cerium oxide nanoparticles

CeO2

Cerium dioxide

DSC

Differential scanning calorimetry

FESEM

Field emission scanning electron microscopy

ROS

Reactive oxygen species

SAED

Selected area electron diffraction

SEM

Scanning electron microscopy

STM

Scanning tunnelling microscopy

TEM/HRTEM

Transmission electron microscopy/high-resolution transmission electron microscopy

TGA

Thermogravimetric analysis

WAXD

Wide-angle X-ray diffraction

XPS

X-ray photoelectron spectroscopy

XRD

X-ray diffraction

References

  1. Annu AA, Ahmed S (2018) Green synthesis of metal, metal oxide nanoparticles, and their various applications. In: Martínez LMT, Kharissova OV, Kharisov BI (eds) Handbook of ecomaterials. Springer International Publishing, Cham, pp 1–45Google Scholar
  2. Arumugam A, Karthikeyan C, Hameed ASH, Gopinath K, Gowri S (2015a) Synthesis of cerium oxide nanoparticles using Gloriosa superba L. leaf extract and their structural, optical and antibacterial properties. Mater Sci Eng C 49:408–415CrossRefGoogle Scholar
  3. Arumugam A, Karthikeyan C, Syedahamed A, Hameed ASH, Gopinath K, Gowri S, Karthika V (2015b) NU synthesis of cerium oxide nanoparticles using Gloriosa superba. Mater Sci Eng C Mater Biol Appl 49:408–415CrossRefGoogle Scholar
  4. Castano CE, O’Keefe MJ, Fahrenholtz WG (2015) Cerium-based oxide coatings. Curr Opin Solid State Mater Sci 19:69–76CrossRefGoogle Scholar
  5. Charbgoo F, Ahmad MB, Darroudi M (2017a) Cerium oxide nanoparticles: green synthesis and biological applications. Int J Nanomedicine 12:1401–1413CrossRefGoogle Scholar
  6. Charbgoo F, Ramezani M, Darroudi M (2017b) Bio-sensing applications of cerium oxide nanoparticles: advantages and disadvantages. Biosens Bioelectron 96:33–43CrossRefGoogle Scholar
  7. Dahle JT, Arai Y (2015) Environmental geochemistry of cerium: applications and toxicology of cerium oxide nanoparticles. Int J Environ Res Public Health 12:1253–1278CrossRefGoogle Scholar
  8. Darroudi M, Javad S, Kazemi R, Ali H (2014a) Food-directed synthesis of cerium oxide nanoparticles and their neurotoxicity effects. Ceram Int 40:7425–7430CrossRefGoogle Scholar
  9. Darroudi M, Sarani M, Oskuee RK, Zak AK, Hosseini HA, Gholami L (2014b) Green synthesis and evaluation of metabolic activity of starch mediated nanoceria. Ceram Int 40:2041–2045CrossRefGoogle Scholar
  10. Darroudi M, Sarani M, Oskuee RK, Zak AK, Amiri MS (2014c) Nanoceria: gum mediated synthesis and in vitro viability assay. Ceram Int 40:2863–2868CrossRefGoogle Scholar
  11. Dutta D, Mukherjee R, Patra M, Banik M, Dasgupta R, Mukherjee M, Basu T (2016) Green synthesized cerium oxide nanoparticle: a prospective drug against oxidative harm. Colloids Surf. B Biointerfaces 147:45–53CrossRefGoogle Scholar
  12. Enghag P (2004) The elements – origin, occurrence, discovery and names. In: Encyclopedia of the elements. Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, pp 55–78CrossRefGoogle Scholar
  13. Gao F, Lu Q, Komarneni S (2006) Fast synthesis of cerium oxide nanoparticles and nanorods. J Nanosci Nanotechnol 6:3812–3819CrossRefGoogle Scholar
  14. Gogoi A, Sarma KC (2017) Synthesis of the novel b -cyclodextrin supported CeO2 nanoparticles for the catalytic degradation of methylene blue in aqueous suspension. Mater Chem Phys 194:327–336CrossRefGoogle Scholar
  15. Gopinath K, Karthika V, Sundaravadivelan C, Gowri S, Arumugam A (2015b) Mycogenesis of cerium oxide nanoparticles using Aspergillus niger culture filtrate and their applications for antibacterial and larvicidal activities. J Nanostruct Chem 5:295–303CrossRefGoogle Scholar
  16. Gusseme BDE, Laing GDU, Hennebel T, Renard P, Chidambaram D, Fitts JP, Bruneel E, Driessche IV, Verbeken K, Boon N, Verstraete W (2010) Virus removal by biogenic cerium. Environ Sci Technol 44:6350–6356CrossRefGoogle Scholar
  17. Hewer TLR, Soeira LS, Brito GES, Freire RS (2013) One-pot green synthesis of cerium oxide-carbon microspheres and their catalytic ozonation activity. J Mater Chem A 1:6169–6174CrossRefGoogle Scholar
  18. Hirano M, Fukuda Y, Iwata H, Hotta Y, Inagaki M (2000) Preparation and spherical agglomeration of crystalline cerium(IV) oxide nanoparticles by thermal hydrolysis. J Am Ceram Soc 83:1287–1289CrossRefGoogle Scholar
  19. Hirst SM, Karakoti AS, Tyler RD, Sriranganathan N, Seal S, Reilly CM (2009) Anti-inflammatory properties of cerium oxide nanoparticles. Small 5:2848–2856CrossRefGoogle Scholar
  20. Husen A (2017) Gold Nanoparticles from plant system: synthesis, characterization and their application. In: Ghorbanpour M, Manika K, Varma A (eds) Nanoscience and plant–soil systems, Springer, vol 48. Cham, Cham Switzerland, pp 455–479CrossRefGoogle Scholar
  21. Hussain I, Singh NB, Singh A, Singh H, Singh SC (2016) Green synthesis of nanoparticles and its potential application. Biotechnol Lett 38:545–560CrossRefGoogle Scholar
  22. Gopinath K, Karthika V, Sundaravadivelan C, Gowri S, Arumugam A (2015a) Mycogenesis of cerium oxide nanoparticles using Aspergillus niger culture filtrate and their applications for antibacterial and larvicidal activities. J Nanostruct Chem 5:295–303CrossRefGoogle Scholar
  23. Kannan SK, Sundrarajan M (2014) A green approach for the synthesis of a cerium oxide nanoparticle: characterization and antibacterial activity. Int J Nanosci 13:1450018CrossRefGoogle Scholar
  24. Kargar H, Ghasemi F, Darroudi M (2014) Bioorganic polymer-based synthesis of cerium oxide nanoparticles and their cell viability assays. Ceram Int 41:1589–1594CrossRefGoogle Scholar
  25. Kargar H, Ghasemi F, Darroudi M (2015) Bioorganic polymer-based synthesis of cerium oxide nanoparticles and their cell viability assays. Ceram Int 41:1589–1594CrossRefGoogle Scholar
  26. Khan SA, Ahmad A (2013) Fungus mediated synthesis of biomedically important cerium oxide nanoparticles. Mater Res Bull 48:4134–4138CrossRefGoogle Scholar
  27. Kilbourn BT (2000) Cerium and cerium compounds. Kirk-Othmer encyclopedia of chemical technology. Wiley, New York, InCrossRefGoogle Scholar
  28. Kumar E, Selvarajan P, Muthuraj D (2013) Synthesis and characterization of CeO2 nanocrystals by solvothermal route. Mater Res 16:269–276CrossRefGoogle Scholar
  29. Li B, Chen Y, Liang W. Mu L, Bridges WC, Jacobson AR, Darnault CJG (2017) Influence of cerium oxide nanoparticles on the soil enzyme activities in a soil-grass microcosm system. Geoderma 299:54–62Google Scholar
  30. Maensiri S, Masingboon C, Laokul P, Jareonboon W, Promarak V, Anderson PL, Seraphin S (2007) Egg white synthesis and photoluminescence of platelike clusters of CeO2 nanoparticles. Cryst Growth Des 7:950–955CrossRefGoogle Scholar
  31. Malleshappa J, Nagabhushana H, Sharma SC, Vidya YS, Anantharaju KS, Prashantha SC, Daruka Prasad B, Raja Naika H, Lingaraju K, Surendra BS (2015) Leucas aspera mediated multifunctional CeO2 nanoparticles: structural, photoluminescent, photocatalytic and antibacterial properties. Spectrochim Acta A Mol Biomol Spectrosc 149:452–462CrossRefGoogle Scholar
  32. Masui T, Hirai H, Imanaka N, Adachi G, Sakata T, Mori H (2002) Synthesis of cerium oxide nanoparticles by hydrothermal crystallization with citric acid. J Mater Sci Lett 21:489–491CrossRefGoogle Scholar
  33. Mittal S, Pandey AK (2014) Cerium oxide nanoparticles induced toxicity in human lung cells: role of ROS mediated DNA damage and apoptosis. Biomed Res Int 2014:1–14CrossRefGoogle Scholar
  34. Munusamy S, Bhakyaraj K, Vijayalakshmi L, Stephen A, Narayanan V (2014) Synthesis and characterization of cerium oxide nanoparticles using Curvularia lunata and their antibacterial properties. Int J Innov Res Sci Eng 2:318–323Google Scholar
  35. Nguyen D, Visvanathan C, Jacob P, Jegatheesan V (2015) Effects of nano cerium (IV) oxide and zinc oxide particles on biogas production. Int Biodeter Biodegr 102:165–171CrossRefGoogle Scholar
  36. Oró D, Yudina T, Fernández-Varo G, Casals E, Reichenbach V, Casals G, González de la Presa B, Sandalinas S, Carvajal S, Puntes V, Jiménez W (2016) Cerium oxide nanoparticles reduce steatosis, portal hypertension and display anti-inflammatory properties in rats with liver fibrosis. J Hepatol 64:691–698CrossRefGoogle Scholar
  37. Patil SN, Paradeshi JS (2016) Bio-therapeutic potential and cytotoxicity assessment of pectin-mediated synthesized nanostructured cerium oxide. Appl Biochem Biotechnol 638–654Google Scholar
  38. Perez JM, Asati A, Nath S, Kaittanis C (2008) Synthesis of biocompatible dextran-coated Nanoceria with pH-dependent antioxidant properties. Small 4:552–556CrossRefGoogle Scholar
  39. Pinjari DV, Pandit AB (2011) Room temperature synthesis of crystalline CeO2 nanopowder: advantage of sonochemical method over conventional method. Ultrason Sonochem 18:1118–1123CrossRefGoogle Scholar
  40. Primo A, Marino T, Corma A, Molinari R, García H (2011) Efficient visible-light photocatalytic water splitting by minute amounts of gold supported on nanoparticulate CeO2 obtained by a biopolymer templating method. J Am Chem Soc 133:6930–6933CrossRefGoogle Scholar
  41. Priya GS, Kanneganti A, Kumar KA, Venkateswara Rao K, Bykkam S (2014) Biosynthesis of cerium oxide nanoparticles using Aloe barbadensis miller gel. Int J Sci Res Publ 4:199–224Google Scholar
  42. Qian J, Chen F, Zhao X, Chen Z (2011) China rose petal as biotemplate to produce two-dimensional ceria nanosheets. J Nanopart Res 13:7149–7158CrossRefGoogle Scholar
  43. Reddy Yadav LS, Manjunath K, Archana B, Madhu C, Raja Naika H, Nagabhushana H, Kavitha C, Nagaraju G (2016) Fruit juice extract mediated synthesis of CeO2 nanoparticles for antibacterial and photocatalytic activities. Eur Phys J Plus 131:154CrossRefGoogle Scholar
  44. Rocca A, Moscato S, Ronca F, Nitti S, Mattoli V, Giorgi M, Ciofani G (2015) Pilot in vivo investigation of cerium oxide nanoparticles as a novel anti-obesity pharmaceutical formulation. Nanomedicine: Nanotechnol Biol Med 11:1725–1734CrossRefGoogle Scholar
  45. Sankar V, SalinRaj P, Athira R, Soumya RS, Raghu KG (2015) Cerium nanoparticles synthesized using aqueous extract of Centella asiatica: characterization, determination of free radical scavenging activity and evaluation of efficacy against cardiomyoblast hypertrophy. RSC Adv 5:21074–21083CrossRefGoogle Scholar
  46. Sathiyanarayanan G, Dineshkumar K, Yang YH (2017) Microbial exopolysaccharide-mediated synthesis and stabilization of metal nanoparticles. Crit Rev Microbiol 43:731–752CrossRefGoogle Scholar
  47. Sharma JK, Srivastava P, Ameen S, Akhtar MS, Sengupta SK, Singh G (2017) Phytoconstituents assisted green synthesis of cerium oxide nanoparticles for thermal decomposition and dye remediation. Mater Res Bull 91:98–107CrossRefGoogle Scholar
  48. Siddiqi KS, Husen A (2017) Recent advances in plant-mediated engineered gold nanoparticles and their application in biological system. J Trace Elem Med Biol 40:10–23CrossRefGoogle Scholar
  49. Siddiqi KS, Husen A, Rao RAK (2018) A review on biosynthesis of silver nanoparticles and their biocidal properties. J Nanobiotechnology 16:14CrossRefGoogle Scholar
  50. Sifontes AB, Gonzalez G, Ochoa JL et al (2011) Chitosan as template for the synthesis of ceria nanoparticles. Mater Res Bull 46:1794–1799CrossRefGoogle Scholar
  51. Sun C, Li H, Chen L (2012) Nanostructured ceria-based materials: synthesis, properties and applications. Energy Environ Sci 5:8475–8505CrossRefGoogle Scholar
  52. Tamizhdurai P, Sakthinathan S, Chen SM, Shanthi K, Sivasanker S, Sangeeth P (2017) Environmentally friendly synthesis of CeO2 nanoparticles for the catalytic oxidation of benzyl alcohol to benzaldehyde and selective detection of nitrite. Sci Rep 7:46372CrossRefGoogle Scholar
  53. Trovarelli A, de Leitenburg C, Boaro M, Dolcetti G (1999) The utilization of ceria in industrial catalysis. Catal Today 50:353–367CrossRefGoogle Scholar
  54. Vinothkumar G, Amalraj R, Babu KS (2017) Fuel-oxidizer ratio tuned luminescence properties of combustion synthesized Europium doped cerium oxide nanoparticles and its effect on antioxidant properties. Ceram Int 43:5457–5466CrossRefGoogle Scholar
  55. Walkey C, Das S, Seal S, Erlichman J, Heckman K, Ghibelli L, Traversa E, McGinnis JF, Self WT (2015) Catalytic properties and biomedical applications of cerium oxide nanoparticles. Environ Sci Nano 2:33–53CrossRefGoogle Scholar
  56. Weeks ME (1932) The discovery of the elements. XVI. The rare earth elements. J Chem Educ 9:1751Google Scholar
  57. Yin L, Wang Y, Pang G et al (2002) Sonochemical synthesis of cerium oxide nanoparticles—effect of additives and quantum size effect. J Colloid Interface Sci 246:78–84CrossRefGoogle Scholar
  58. Zhang F, Chan S-W, Spanier JE, Apak E, Jin Q, Robinson RD, Herman IP (2002) Cerium oxide nanoparticles: size-selective formation and structure analysis. Appl Phys Lett 80:127–129CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Annu
    • 1
  • Akbar Ali
    • 1
  • Rahul Gadkari
    • 2
  • Javed N. Sheikh
    • 2
  • Shakeel Ahmed
    • 3
  1. 1.Department of ChemistryJamia Millia IslamiaNew DelhiIndia
  2. 2.Department of Textile TechnologyIndian Institute of TechnologyNew DelhiIndia
  3. 3.Department of ChemistryGovernment Degree College MendharMendhar, JammuIndia

Personalised recommendations