Experimental Design

  • Ratna Tantra


A key aspect of being a research scientist lies in your ability to design an experiment and to design it well. By adopting the correct approach to experimental design, you will be reducing/removing any unwanted errors that can influence experimental results. In this chapter, I will cover the basics and discuss in more details the five phases involved when you design your experiments. Out of the five phases, it is how you define your scientific procedure that is key and will ultimately govern the quality of your final results. There are two common strategies that you can adopt and thus the chapter discusses:
  • How to run a control experiment.

  • How to adopt a design of experiment (DOE) approach.

I will show you, with the aid of a case study, how the two approaches differ from one another. Although running a control experiment is more straightforward to conduct (compared to adopting the DOE approach), its major limitation is that it does not take into account real-world scenarios, in that it is unable to handle the interactions between two or more variables.


Hypothesis Variables Control experiment Design of experiment Surface-enhanced Raman spectroscopy 


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Ratna Tantra
    • 1
  1. 1.PortsmouthUK

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