Toxicity and Safety Evaluation of Nanoclays

  • Adriano BrandelliEmail author


The term nanoclay is often associated to the natural clay minerals that contain silica and alumina as the main components. Nanoclays have been frequently incorporated into polymeric systems, resulting in nanocomposites that display a significant enhancement in barrier properties besides improved thermal and mechanical resistance. Recent studies describe the potential use of nanoclays as drug carriers and as modulators of drug release. Because of the increase in manufacturing of nanoclay-containing products, including an extensive array of industrial applications, information on the toxicological and health effects of nanoclay exposure is necessary. Methods conventionally used for evaluation of nanoparticles can be employed or adapted for toxicity evaluation of nanoclay materials. In vitro systems based on biochemical and cell culture methods and in vivo evaluation using lower organisms and animal models are used to access the potential toxicity of nanoclays. Most studies indicate that nanoclays are relatively safe and toxicity is often associated to nanoclay functionalized with organic modifiers.


Montmorillonite Halloysite Toxicity evaluation Food packaging 


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© Springer Nature Switzerland AG 2018

Authors and Affiliations

  1. 1.Centro de Nanociência e NanotecnologiaUniversidade Federal do Rio Grande do SulPorto AlegreBrazil

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