Status Epilepticus in Adults

  • Fabio MinicucciEmail author
  • Matteo Impellizzeri
  • Giovanna Fanelli


In electroencephalography books, relative significance is given to “status epilepticus” (SE), maybe because of the idea that it could only be a simple repetition of seizures in a very short time from one another. Actually, at least two factors contribute making the EEG patterns of SE much more complex: the first is the overlapping of the transients related to the seizures with those related to underlying disease, and the second is the EEG modification related to a sustained or prolonged status epilepticus. The EEG of the SE can thus follow its graphic expression which is different from that of single seizures repeated over time, coming up to express critical patterns that are not always easily recognizable. The elements of pathophysiology and clinical electroencephalographic practice show that the SE is a dynamic pathological process that expresses itself in a different manner from patient to patient depending on its etiology, duration, topographic extension, clinical manifestation, and therapeutic interventions that are carried out. The proposed classification of SE in 2015 (Trinka et al., Epilepsia 56(10):1515–23, 2015) establishes the importance of EEG in the diagnosis and management of the SE by including the EEG axial description to define a correct classification of the patient.


Status epilepticus EEG Nonconvulsive status epilepticus (NCSE) Ictal-interictal continuum 



A special thanks to the EEG technicians of San Raffaele Hospital of Milan, Alessandra Amato, Sara Bruno, Aldo Elia, Claudia Paleari, and Amelia Tirelli, for the competence in carrying out of the exams. We also mentioned Laura Schieppati e Lucrezia Nava for English translation of the text and Marco Vabanesi and Marco Cursi for the relevant contribution to the activity of our laboratory.


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Fabio Minicucci
    • 1
    Email author
  • Matteo Impellizzeri
    • 2
  • Giovanna Fanelli
    • 2
  1. 1.Department of NeurologyChief of Epilepsy Center, Ospedale San RaffaeleMilanItaly
  2. 2.Department of NeurologyOspedale San RaffaeleMilanItaly

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